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Biomedical subjects

L Parsons

Publications and source records attributed to L Parsons.

61 records · Page 4Linked to original sources
PubMed1966

Agrobacterium tumefaciens Conn. 3. Effect of thermal shock on bacteria in relation to tumorinducing ability.

Stonier, Tom (Manhattan College, Bronx, N.Y.), Robert E. Beardsley, Lowell Parsons, and James McSharry. Agrobacterium tumefaciens Conn. III. Effect of thermal shock on bacteria in relation to tumor-inducing ability. J. Bacteriol. 91:266-269. 1966.-Bacteria heated to 42 C for 30 min exhibit a decrease in tumor-initiating ability without a detectable loss in viability. The thermal shock inhibits subsequent bacterial growth for up to 1.5 hr. As bacterial growth recovers, so does tumor-initiating ability. Respiration of the culture is somewhat increased by the heat treatment. The data suggest that living, actively respiring bacteria do not induce tumors unless they are also growing. The results also point to the necessity for excluding bacterial growth inhibition when interpreting data on the effect of various agents on tumor initiation.

Hot Temperature↗
PubMedDate not supplied

A four-dimensional probabilistic atlas of the human brain.

The authors describe the development of a four-dimensional atlas and reference system that includes both macroscopic and microscopic information on structure and function of the human brain in persons between the ages of 18 and 90 years. Given the presumed large but previously unquantified degree of structural and functional variance among normal persons in the human population, the basis for this atlas and reference system is probabilistic. Through the efforts of the International Consortium for Brain Mapping (ICBM), 7,000 subjects will be included in the initial phase of database and atlas development. For each subject, detailed demographic, clinical, behavioral, and imaging information is being collected. In addition, 5,800 subjects will contribute DNA for the purpose of determining genotype- phenotype-behavioral correlations. The process of developing the strategies, algorithms, data collection methods, validation approaches, database structures, and distribution of results is described in this report. Examples of applications of the approach are described for the normal brain in both adults and children as well as in patients with schizophrenia. This project should provide new insights into the relationship between microscopic and macroscopic structure and function in the human brain and should have important implications in basic neuroscience, clinical diagnostics, and cerebral disorders.

Adolescent↗
PubMedDate not supplied

Office management of minor burns.

About 2 million people are burned in the United States each year. About 80% of these are treated as outpatients. Flame burns are the most common type of burn injury in adults, and scald burns are the primary type in children. Primary care providers must be familiar with burn assessment so burn injuries can be triaged appropriately to a regional burn center, an acute care (facility, or office management. Assessment includes extent and depth of burns, location of burns, patient reliability, and the home situation. Office management involves emergency care, debridement and dressings, topical antimicrobials, and pain control. Patient education for care in the home environment is essential for optimal healing.

Adult↗