Ultrasound assessment of gallbladder filling in presence or absence of pharmacologically stimulated biligenesis.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to L Parisi.
Explore the source record for details and available documents.
Three cases of cystic dilatation of the biliary tract of 1st, 4th and 5th type are reported here according to the classification established by Longmire and Hadad amended. In two patients the diagnosis was carried out through ultrasound examination and confirmed, in one case, by intraveinous cholangiography associated to computed tomography (and by peroperatory cholangiogram in the other one). In the third patient suffering from Caroli's disease the diagnosis was carried out during peroperating cholangiography. The possibilities of the different methods in diagnosing cystic dilatations of the biliary tract are discussed and therapeutic problems are taken into consideration.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Seventy-eight patients with clinical findings pointing to possible polycystic ovarian disease (POD) were studied by ultrasound examination. The endocrine status of each patient was evaluated by assay of blood progesterone levels and gonadotropin luteinizing hormone and follicle-stimulating hormone (LH-FSH), both under basal conditions and after luteinizing hormone releasing factor (LH-RH) and androgen hormone stimulation (testosterone and 17-ketosteroids under basal conditions and after a suppression test with dexamethasone). POD was diagnosed in nine cases and confirmed in four at operation. Ultrasound examination as an aid to POD diagnosis is discussed and its value underlined as a precise method in determining ovarian size, shape, and structure, and as a follow-up for patients after surgery.
One hundred and eight patients presenting clinical symptoms of prostatic disease have been studied by suprapubic echography, with comparison of clinical and echographical diagnoses with the results shown by histological examination. The authors found the diagnosis by echography to be quite precise, not significantly differing from the results given by histological examination, in contrast to those diagnoses based on clinical examination. Describing the echographic pictures found in benign hypertrophy of the prostate of which a previously uninterpreted nodular picture is resorted (intra- and extra-capsular neoplasms and chronic prostatis) the authors conclude by proposing suprapubic echography as an initial instrumental approach in the diagnosis of prostatic diseases.
Explore the source record for details and available documents.
The authors report the principle data resulting from the study of 43 patients presenting pulsating abdominal masses: 21 aneurysms of the aorta have been documented, and the comparative results between echography and angiography compared with operatory findings in 15 patients. With echography, reliable diagnostic precision regarding the form and dimensions of the aneurysmatic cavity is possible, and above all, the exclusion or confirmation of the presence of blood clots is allowed. The vascular situation, especially of the principle collateral branches, is better defined by aortography. Echography offers advantages not only in the survey of patients with high operation risk aneurysms, and other pulsating abdominal masses as well, but brings into evidence retroperitoneal fibrosis circumscribing the aneurysm. Last, it is preferable in the follow up of vascular prosthesis after surgery.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Extracardiac anomalies (ECA) occur in 25% of infants seen during the first year of life for significant cardiac disease. Often the ECA are multiple and one third of the affected infants have some established syndrome. In infants with endocardial cushion defect, patent ductus arteriosus, atrial septal defect, ventricular septal defect, malpositions, tetralogy of Fallot, and complex coarctation ECA occur in 25% or more of the cases. The most frequent ECA are in the musculoskeletal system or associated with a specific syndrome. The presence of an ECA significantly increases the mortality in infants with CHD.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
To evaluate the efficacy and safety of gabapentin in the treatment of muscle cramps, we engaged an open-label trial with a group of 30 patients with frequent (> 5 cramps/week), stable, long-lasting cramps, associated with different diseases. Gabapentin was effective in reducing the frequency and severity of muscle cramps and associated sleep disturbances (clinical outcome measures) within the first 2 weeks of medication at 600 mg/d. At the 1 month control (mean dosage, 825 +/- 35 mg), almost every patient had responded to treatment and two thirds experienced a total remission of symptoms. After 3 months of therapy (mean dosage, 892 +/- 180 mg), cramps disappeared in 100% of patients and this benefit persisted as long as 6 months. Additionally, we evaluated in 10 patients the Cramps Threshold Frequency (CTF) (neurophysiological outcome measure) before and during gabapentin treatment. Gabapentin significantly increased the CTF, returning it to normal values. With the limitation of an open-label methodology, our clinical and neurophysiologic experience suggests that a gabapentin dose of 600-1200 mg/d would be helpful in the treatment of muscular cramps.
PURPOSE: To evaluate the ability of scanning laser polarimetry (SLP) with a fixed corneal polarization compensator (GDx-FCC Nerve Fiber Analyzer) compared to one with a variable one (GDx-VCC) in the discrimination between healthy and early glaucomatous eyes. METHODS: Forty patients with early glaucomatous visual field defects, having a mean deviation of 3.1-/+1.6 dB and a pattern standard deviation of 3.1-/+0.9 dB, and 40 controls underwent both GDx-FCC and GDx-VCC. One eye per patient was considered. The cut-off point, taken as the value dividing healthy from glaucomatous eyes with highest probability, was determined for each GDx parameter. Linear discriminant functions (LDFs) were separately developed for GDx-FCC and GDx-VCC parameters. Sensitivity, specificity, and area under the receiver operating characteristic curve (AROC) for discriminating between healthy and glaucomatous eyes were calculated for each GDx parameter, both according to the GDx normative database and after the selection of new cut-off points, and for the LDFs. RESULTS: All software-provided parameters showed low sensitivity and high specificity. The selection of new cut-off points improved the performance of all GDx parameters: VCC parameters performed better than FCC parameters; the largest AROCs were associated with the superior/nasal ratio for the GDx-FCC (0.86) and with the Number for the GDx-VCC (0.87). The LDFs provided an AROC of 0.89 with both the GDx-FCC and the GDx-VCC parameters. CONCLUSIONS: The GDx-VCC showed a higher ability in the early diagnosis of glaucoma when compared with the GDx-FCC. The individuation of the right cut-off point of selected parameters with both GDx settings performed better than the software-provided parameters, and comparably to the GDx parameters-based LDFs.