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Biomedical subjects

L Papez

Publications and source records attributed to L Papez.

At least 37 records · Page 2Linked to original sources
PubMed1977

[Cytologic evaluation of the hormonal state in female with breast tumours (author's transl)].

Physiologic changes, growth, differentiation, and involution of the female breast are closely connected to the endocrine activity of the ovary. We examined the relationship of progesteron and oestrogen in 69 women with tumours of the breast. Histology revealed benign tumours in 18 and malignant tumours in 51 patients. Both groups showed distinct alterations in hormonal cytology of the vaginal smear. Statistical evaluation of the findings gives hints of a hormonal imbalance. There is a relative increase of oestrogenic activity and a lack or a decrease of gestagenic activity in women before menopausis. In postmenopausal and old women, neoplasms of the breast are accompanied by signs of proliferative activity as shown by the laboratory data.

Adult↗
PubMed1977

Determination of L-lactate: NAD+ - oxidoreductase (E.C.1.1.1.27) and its isoenzymes during pregnancy.

In the First Gynaecology and Maternity Clinic of the Faculty of Medicine, Charles University Prague, we investigated total serum LDH (L-lactate: NAD-oxidoreductase, E.C.1.1.1.27) activity and that of its 5 isoenzymes during physiological pregnancy. We divided our pregnancies, for practical purposes, into 3 groups. The first comprised women in the 10th-to 20th week of pregnancy, the second women in the 20th to 30th week and the third women in the 30th to 40th week. In each group we took blood dynamically at regular 14-day intervals from the same women, with the aim of assuring the maximum possible homogeneity of the tested material (blood) in correlation to time. We found that, during physiological pregnancy, neither the total LDH activity level, nor that of its five fractions, exceeded the norm determined for the Czechoslovak population. The activities fluctuated typically during pregnancy, however, within the framework of the norm. Some agreement was found between changes in LDH activity and changes in the chorionic gonadotrophin level.

Female↗