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Biomedical subjects

L Palombi

Publications and source records attributed to L Palombi.

67 records · Page 4Linked to original sources
PubMedDate not supplied

[Borderline arterial hypertension. Preliminary study of a young Roman population].

Blood pressure levels and related factors such as age, sex, body mass index, socioeconomic level and family were studied in a group of 398 young subjects. A high incidence of subjects with borderline hypertension was confirmed. The results analysed and discussed the conclusion being reached that the form of arterial hypertension may be considered as either the onset or at least a risk factor or stable hypertension.

Adolescent↗
PubMedDate not supplied

[Dental health and the state of oral hygiene in an elderly population in Rome].

The purpose of this study was to investigate dental conditions and oral hygiene in a population of 369 elderly people residing in Rome--293 females and 76 males--aged between 60 and 99 years (mean 81.9 +/- 8.1). The sample was interviewed following a dental examination. Clinical tests revealed that 40% were totally edentulous, whereas subjects with natural teeth had a mean of 11.4, teeth, of which 1.5 were decayed. Oral hygiene habits were investigated by means of questions on use of dental tools (toothbrush, mouth-wash, dental floss), which were not much used. Moreover, many elderly people reported they had not been to the dentist's recently (86.2% during the last year) because they did not feel it necessary. From this study a rather low level of oral health has emerged, along with a limited knowledge of prevention for dental and periodontal diseases. These results show the need of dental treatment and prevention for the elderly population.

Age Factors↗
PubMedDate not supplied

Differentiation of glioblastoma multiforme from astrocytomas by in vitro 1H MRS analysis of human brain tumors.

In vitro high resolution 1H NMR spectroscopy allows non-invasive metabolic evaluation of specimens derived from surgically biopsied or resected brain tumors, with the aim of identifying potential markers of different malignancy grading, and improving diagnostic and therapeutic strategies. In the present study we evaluated 36 patients affected by different brain gliomas (7 well differentiated astrocytomas, 7 anaplastic astrocytomas, 16 glioblastomas, 6 oligodendrogliomas). These analyses allowed discrimination between well differentiated and anaplastic astrocytomas (AII + AA) and glioblastoma multiforme (GM) samples on the basis of the ratio between the integrated choline-containing resonance (b"Cho") and the creatine peaks (creatine (Cr) + Phosphocreatine (PCr)). While no definite difference was found between AII and AA, significantly higher values were observed for this ratio in GM. Other signals, derived from different metabolites, such as Glycine (Gly) and N-acetyl-aspartate (NAA), may also assume relevance in differential tumor diagnosis. In this study an increased [Gly]/[Cr + PCr] ratio was observed in GM with respect to AII and AA. The NAA levels observed in our tumor specimens may be explained on the basis of tumor cell infiltration into brain adjacent tissue. Interesting, but inconclusive, are the data concerning oligodendrogliomas, which, also in well differentiated forms, exhibit increased levels of b"Cho"/(Cr + PCr) ratio. The present study confirms the role of MRS in the biochemical characterization of neoplastic brain tissue and its potential contribution to a better selection of multidisciplinary treatment strategies.

Astrocytoma↗
PubMedDate not supplied

Disability and the need for rehabilitative facilities in the young Albanian population of the Lezha district.

In order to implement a community-based rehabilitation programme in the rural district of Lezha (Albania), a systematic survey to assess disabilities and related care needs of people under 18 years of age was carried out. The aim of the survey was to evaluate the prevalence rates and severity of disabilities, detected by means of a questionnaire issued by the WHO Community-Based Rehabilitation Programme. The prevalence of disabled people under 18 years of age was 5.86 per 1000 (180 subjects out of the estimated population of 30,712). The most frequent diagnosis was sequelae of infantile cerebral palsy (1.8 per 1000), followed by mental retardation and deafness. The results of the survey stress that the severe non-self sufficiency of these subjects could be improved by means of an appropriate programme to increase their autonomy, including rehabilitation treatment and early school attendance.

Adolescent↗