Thiophosphate labelling of mitochondria-lack of evidence for an acyl-phosphate intermediate in oxidative phosphorylation.
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Animals↗
Biomedical subjects
L Packer
Publications and source records attributed to L Packer.
Oscillatory states of mitochondria. Studies on the oscillatory mechanism of liver and heart mitochondria.
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Acetates↗
Monolayer culture techniques for normal human diploid fibroblasts.
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Cell Count↗
Changes in membrane lipid structure of illuminated chloroplasts: studies with spin-labeled and freeze-fractured membranes.
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Biological Transport↗
Retention of K+ gradients in imidoester cross-linked erythrocyte membranes.
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Adipates↗
Extension of the lifespan of cultured normal human diploid cells by vitamin E.
Inclusion of vitamin E (DL-alpha-tocopherol) in the culture medium for human diploid cells greatly prolongs their in vitro lifespan. The addition of 100 mug of DL-alpha-tocopherol per ml of medium has allowed us to culture WI-38 cells for more than 100 population doublings to date. (These cells normally have an in vitro lifespan of 50 +/- 10 population doublings.) Cells at the 100th population doubling have a normal diploid karyotype, appear to behave in all other respects like young WI-38 cells, and are still actively dividing. We interpret this result as support for the free radical theory of aging.
Cell Division↗
Studies on mitochondrial proteins. I. Separation and characterization by polyacrylamide gel electrophoresis.
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Adenosine Monophosphate↗
Mobility of membrane particles in chloroplasts.
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Acetates↗
Freeze-fracture studies on mitochondria from wild-type and respiratory-deficient yeasts.
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Adenosine Triphosphatases↗
Role of lipids in mitochondrial energy coupling: evidence from spin labeling and freeze-fracture electron microscopy.
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Animals↗
Relation of unsaturated fatty acid composition of rat liver mitochondria to oscillation period, spin label motion, permeability and oxidative phosphorylation.
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Acetates↗
Action of the neurotoxin -N-oxalyl-L- , -diaminopropionic acid on glutamate metabolism of brain mitochondria.
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Amino Acids↗
Functional organization of intramembrane particles of mitochondrial inner membranes.
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Animals↗
Thiophosphate as a probe for mitochondrial oxidative phosphorylation, model phosphorylation reactions and membrane permeability.
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Adenosine Triphosphate↗
Aldehyde oxidation in rat liver mitochondria.
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Adenosine Diphosphate↗
Effect of sucrose and uncouplers on lipid spin labeling of mitochondria.
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Aldehydes↗
Methods for the measurement of chloroplast volume and structure in vitro and in vivo.
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Chloroplasts↗
Spin labeling studies of the effect of ATP, Mg 2+ on mitochondrial membranes.
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Adenosine Triphosphate↗