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Biomedical subjects

L P Vorob'ev

Publications and source records attributed to L P Vorob'ev.

At least 19 recordsLinked to original sources
PubMed2000

[Motor and secretion function of stomach and duodenum, duodenogastric reflux in patients with duodenal ulcer].

Gastric secretion, motor function and tonicity of the stomach and duodenum, duodenogastric reflux were studied in inpatients with two clinicopathogenetic types of duodenal ulcer: observed at young age (type 1) and in later life (type 2). The examination included pH-metry with simultaneous balloon cimography, chromogastroduodenoscopy with Kongo-red, tests for Helicobacter pylori conducted on the biopsy samples. All the patients were found to have continuous acid production. High acid production was more frequently registered in males with the disease type 1, the lowest production was in females with the disease type 2. Duration of the acid inflow into the duodenum in patients with the disease type 2 was greater than that in young subjects. Mild ulcer was associated with moderate acidity in the duodenum, in severe ulcer the acidity was very high. Males with the disease 1 and 2 and females with type 2 had hyperkinetic, hypertonic gastric motor function. In duodenal ulcer prevalent is hypertonic, hyperkinetic type of duodenal motor function being most frequent among males with the disease type 2. Duodenogastric reflux occurs more often in patients with intensive acid production associated with hypotonic, hypokinetic motor type and duodenal tone.

Adult↗
PubMed1996

[The role of different investigations in diagnosis of functional disorders of the biliary system].

The paper presents the results obtained upon examination of inpatients with various types of biliary dyskinesia. The examination included: fraction chromatic duodenal intubation, stepwise manometry, cholecystography, ultrasound investigation of the liver, gall bladder, biochemical tests of the bile. Fraction duodenal intubation discovered gall bladder dysfunction. The manometry was necessary for diagnosis of duodenal hypertension. X-ray revealed primary defects in gall bladder motility. It is concluded that the diagnosis of functional disorders implies combined clinical and instrumental modalities.

Adolescent↗
PubMed1995

[Evaluation of pulmonary hypertension by dopplerography in patients with nonspecific pulmonary diseases].

Doppler echocardiography was used to quantify pulmonary hypertension and phase pattern of right heart systole in 140 patients with nonspecific pulmonary diseases to study hemodynamic characteristics of pulmonary circulation and right heart as well as external respiration. There appeared a relationship between the severity of pulmonary hypertension, bronchial obstruction and arterial hypoxemia. It seems that in nonspecific pulmonary diseases hemodynamic changes arise prior to functional disorders of external respiration.

Adolescent↗
PubMed1994

[Characteristics of external respiration function and pulmonary circulation in patients with ischemic heart disease complicated by disorders of intraventricular conduction].

The authors provide evidence on the condition of external respiration and hemodynamic shifts in the lesser and greater circulation in coronary patients with bundle-branch block; establish early objective quantitative criteria of the diagnosis of hemodynamic impairment arising in formation of the above blocks basing on ECG, phonocardiography, echocardiography findings; compare hemodynamic effects of single-dose nitrosorbide and corinfar in the above patients. Nitrosorbide and corinfar correct hemodynamics and external respiration, the former being more effective in normalizing the greater, while corinfar the lesser circulation.

Adult↗
PubMed1994

[The possibilities of using intermittent normobaric hypoxia for treating hypertension patients].

The response to intermittent normobaric hypoxia (INH) created in breathing gas hypoxia mixture (10% oxygen, 90% nitrogen) was evaluated in 123 patients with essential hypertension stage I and II. Hypoxia adaptation effects on central hemodynamics, physical performance, kinetics of oxygen exchange were studied. A pronounced response to INH persistent for 6 months was demonstrated in 80.5% of the patients. The reduction of the arterial pressure resulted from different mechanisms depending on hemodynamic type. Physical performance of the patients rose, oxygen consumption and transport normalized.

Adult↗
PubMed1993

[Cardiorespiratory disturbances in atrioventricular block].

The paper covers questions of the emergence and progressing of cardiorespiratory disturbances in coronary patients with defective atrioventricular conduction. The authors characterize central and peripheral hemodynamics in the above patients, diastolic ventricular filling, external respiration, the disturbances of which were studied in correlation with hemodynamic features and lipid peroxidation. The patients were examined for effects on their cardiorespiratory system of cardioselective beta-blockers, adrenomimetics, antioxidants, membrane stabilizers.

Echocardiography, Doppler↗
PubMed1993

[The correction of motor-tonic disorders of the gastrointestinal tract and of duodenogastric reflux with laser radiation].

Forty-five patients with duodenogastric reflux and defective gastroduodenal motor tonicity (gastroduodenal hypotonia, duodenal hypertension, gastric hypotonia in combination with duodenal hypertension) were exposed to He--Ne laser radiation. The impact was focused on the biologically active points G14, TR5, VC15, E21. The treatment resulted in normalization of the gastrointestinal pressure gradient, in discontinuance or reduction of duodenogastric reflux.

Acupuncture Points↗
PubMed1993

[Adaptational reactions in patients with acute pneumonia].

Adaptive reactions were studied in 80 patients with acute pneumonia. In the hospital 94.1% patients showed reactions of stress and incomplete reactions of training and activation. With improvement of the clinical condition the number of stress reactions reduces, while the number of physiological reactions of training and activation increased. The stress reaction is an unfavourable factor as to transition of acute pneumonia into chronic unspecific pulmonary diseases. These studies may be of value for evaluation of the prognosis and care of acute pneumonia.

Acute Disease↗
PubMed1992

[Doppler echocardiographic assessment of left atrial and left ventricular function during right bundle branch block].

Electrocardiographic, echocardiographic and Doppler echocardiographic studies were performed in 44 patients with coronary heart disease and complete right bundle branch block. The patients were found to have an impaired phase pattern of left ventricular systole and diastole as more prolonged length of its isometric relaxation and contraction, lower economic feasibility and efficiency of its contraction, moderate dilation and hypertrophy. Hemodynamic abnormalities in the left heart in these patients are closely correlate with the changes in the phase pattern of right ventricular systole and they turn out to be so greater as the degree of its hypertrophy is. In complete right bundle branch block, left ventricular pump dysfunction leads to decreased cardiac output and cardiac index, increased total peripheral vascular resistance, thus predisposing to impaired greater circulation.

Adult↗
PubMed1992

[The clinico-electrocardiographic classification of the early ventricular repolarization syndrome].

Based on an analysis of 4980 ECGs of patients, the authors could distinguish and classify the clinico-electrocardiographic versions of the early ventricular repolarization syndrome (EVRS): permanent, occurring for the first time, suddenly disappearing, intermittent with a gigantic T wave; with a negative T wave, with a short-term T wave inversion, marked by the combination with Wolff-Parkinson-White syndrome, and additional chordae of the left ventricle. The clinico-electrocardiographic classification of the EVRS is of paramount importance for practitioners owing to an assumption that the EVRS is not only a version of the normal ECG but also can be a marker of CHD. The authors view the EVRS as an independent version of the preexcitation syndrome along with Wolff-Parkinson-White and CLK syndromes, with the manifestations of which it may combine.

Diagnosis, Differential↗
PubMed1992

[The function of the left heart in blockade of the left bundle of His].

A complex Doppler echocardiographic study was performed in 134 patients with complete block of the left bundle branch, its anterior branch or with concurrence of these two types of intraventricular conduction disturbance. The authors identified 5 types of paradoxical ventricular septal motion, which were related to the specific features of intraventricular asynchronism and ventricular electric systole. Type I shows the greatest decrease in left ventricular contractility, left atrial overload and phasic destruction of left ventricular systole, which reflects the processes of depolarization and repolarization propagation in the myocardium. Type IV is characterized by the lowest number of hemodynamic abnormalities. Cardiac hemodynamics is also related to the type of intraventricular block, being the least changed in isolated anterior left bundle-branch and the most changed in concurrent anterior branch and entire left bundle-branch block.

Adult↗
PubMed1992

[Evaluation of the effectiveness of laser and drug therapy of patients with duodenal ulcer].

The paper presents clinical and morphological assessment of therapeutic response in 97 patients aged from 20 to 65 years with the diagnosis of duodenal ulcer from 1 to 15 years. Routine treatment was performed in 32 and drug therapy in combination with local He-Neon radiation of the ulcer was performed in 65 patients. Higher therapeutic response especially in those with the disease duration not longer than 5 years was revealed in case of laser therapy versus the routine drug treatment. The effect of laser radiation either on the ulcer mucous coat or far from it resulted in a moderation of inflammatory and an increase of reparative processes. More rapid terms of ulcer healing is of a certain time-saving effect.

Adult↗