Search PubMed⌕ Search

Biomedical subjects

L P Semenova

Publications and source records attributed to L P Semenova.

At least 19 recordsLinked to original sources
PubMed2003

[The cell composition in the lymphocyte population and the radiation adaptive response].

Using lymphocytes of 5 healthy individuals the ability to adaptive response (AR), cell composition of population after PHA stimulation, changes in cell composition population after irradiation in the dose of 1.0 Gy and after irradiation in adaptive (0.05 Gy) and challenge (1.0 Gy) doses have been studied. AR observed in 2 of the 5 individuals only. After PHA stimulation the persons with AR have the total amount of cells after mitosis or during mitosis (the number of binucleated cells + the number of multinucleated cells + the whole cells with micronuclei + the number of mitotic cells) on average is higher than in persons without AR. In individuals with AR the linear correlation between the number of binucleated cells with micronuclei (on the 1000 scored binucleated cells) and the part of binucleated cells in the population is observed with coefficients of correlation -0.89 and -0.91. In the humans without AR this correlation is absent. The correlation observed permits to suppose that AR may occur at the expense of not only the decrease in number of damaged lymphocytes, but also the increase in the share of not damaged binucleated cell with the stable number of damaged cells.

Adaptation, Physiological↗
PubMed1988

[Inability of large granular lymphocytes to recirculate through blood-lymph barriers].

The level of large granular lymphocytes (LGL) has been determined in thoracic lymph duct and peripheral blood of cattle. It has been shown that in contrast to the blood, these cells are present in the lymph in minor quantities. Unlike blood LGL, lymph LGL have smaller granules in cytoplasm. It is concluded that LGL do not recirculate from blood to central lymph.

Animals↗
PubMed1987

[Human Bifidobacterium flora, its normalizing and protective functions].

The paper is concerned with investigation of the normalizing and protective role of the Bifidobacterium flora in humans and its quantitative predomination in intestinal microbiocenosis of children and adults. The data on antagonistic properties of bifidobacteria with respect to pathogenic and facultative pathogenic bacteria, the Bifidobacterium flora influence on the host metabolism and efficiency of bifidobacterin in recovery of the Bifidobacterium flora optimal level are presented.

Adult↗
PubMed1977

[Dynamics of the establishment of intestinal microflora in healthy full-term newborns].

A study was made of the dynamics of establishment of the intestinal microflora in 79 healthy mature neonates born of healthy mothers. A total of 223 bacteriological examinations were conducted. A stable prevalence of bifidobacteria over the aerobic portion of the intestinal biocenosis occurred in all the children from the 8th day after birth. Along with this the following bacteria were continuously present in the intestine: lactic bacilli and streptococci E. coli, enterococci and staphylococci; however, their portion in the biocenosis was not great. Bacteroids, microbes of the Proteus genus, and yeast-like fungi were found in the cultures only before the establishment of a high bifidobacteria level. Conditionally pathogenic microorganisms and their associations were continuously revealed in 19.8% of healthy mature neonates. Apparently the qualitative prevalence of bifidobacteria prevented the clinical expression of dysbacteriosis in these children.

Age Factors↗