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Biomedical subjects

L P Noel

Publications and source records attributed to L P Noel.

At least 19 recordsLinked to original sources

Retinal complications of strabismus surgery.

The frequency of inadvertent retinal perforation during routine strabismus surgery has been debated, as patients with such complications are usually asymptomatic. Recent prospective clinical studies indicate a retinal perforation rate of 0.4 to 2.8 per 100 cases using modern surgical techniques and materials. Laboratory studies support close follow-up without treatment as an acceptable mode of management in the majority of these cases.

Animals↗

Natural history of presumed congenital Brown syndrome.

OBJECTIVE: To evaluate the stability of the ocular alignment in patients with presumed congenital Brown syndrome. DESIGN: A retrospective review of patients with Brown syndrome with an emphasis on nonsurgical cases. Follow-up of at least 1 year was required for inclusion in the study. SETTING: Patients were selected for this study from the pediatric ophthalmology services at the Ivey Institute of Ophthalmology, London, Ontario, and the Children's Hospital of Eastern Ontario, Ottawa. PATIENTS: A cohort of 71 patients with presumed congenital Brown syndrome. Two cases were bilateral. Eleven cases were excluded because of insufficient length of follow-up, leaving 60 patients with an average follow-up of 46 months. All patients were assessed and followed up by a pediatric ophthalmologist. RESULTS: Of 38 patients who had no hypotropia in primary position at presentation, only two (5%) patients experienced a worsening with the development of a small vertical strabismus during the follow-up period. Six (10%) of the entire group of 60 patients experienced a complete spontaneous resolution of the deficiency in elevation at 4, 6, 8, 10, 12, and 15 years of age. CONCLUSION: Among patients with congenital Brown syndrome, those who are orthotropic in the primary position tend to remain stable or improve over time without surgical intervention.

Child↗

Chloroma.

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Child↗

Sodium citrate in paediatric outpatients.

To determine whether the gastric content pH of paediatric patients could be raised in an effort to decrease post-aspiration morbidity and mortality, the antacid sodium citrate (0.4 ml.kg-1) was given preoperatively to 25 patients aged 1 to 14 (6.0 +/- 3.5, mean +/- SD) years. Their gastric content pH was measured following induction of anaesthesia. These values were compared to those obtained from a control group (n = 20) ranging in age from seven months to nine (3.3 +/- 2.7) years. A gastric content pH value of greater than 2.5 was measured in 23 of the 25 patients who received sodium citrate. There were only two patients in the control group with a gastric content pH greater than 2.5, p less than 0.001, Fisher exact test. Only one child refused to take the medication. The administration of sodium citrate appears to be an effective method of raising the gastric content pH in paediatric patients.

Ambulatory Care↗

Traumatic hyphema in children.

The authors reviewed the medical records of 316 children admitted between January 1977 and March 1985 with a diagnosis of traumatic hyphema. In this group of patients, 1 to 17 years old treated without antifibrinolytics, the incidence of secondary hemorrhage was 7.6% (24 of 316 patients) of whom three required surgical evacuation of the clot. The risk of rebleeding did not correlate with the patient's age, use of topical steroids, or cycloplegics. Of 176 patients followed from 1 month to 7 years post-hospital discharge, 91% achieved 20/30 vision or better, but only 77% of the patients with secondary hemorrhage attained this level of vision. Amblyopia, a potential threat in young children, occurred in only two children both of whom also required cataract extraction. From our captive pediatric population of 228,000 the incidence of traumatic hyphema is 17 per 100,000 children per year.

Adolescent↗

Check ligaments: surgical effects in infantile esotropia.

In a prospective randomized study, we compared the results of surgical treatment of 25 patients with infantile esotropia, using bilateral medial rectus muscle recession of a graded amount without severing the check ligaments, to results obtained with a similar group of 23 patients in whom check ligaments were severed at the time of bimedial surgery. No significant difference could be found in the immediate postoperative and 6-month postoperative ocular alignment of the two groups.

Axis, Cervical Vertebra↗

The oculocardiac reflex during ophthalmoscopy in premature infants.

Of 54 consecutive infants referred for ophthalmoscopy with the pupils dilated, continuous electrocardiographic monitoring showed that 17 (31%) had bradycardia, ranging from 10% to 59% of baseline, coincident with instillation of eyedrops, insertion of an eyelid speculum, pressure on the globe, or stretching of the medial and lateral recti muscles.

Arrhythmias, Cardiac↗

Ocular involvement in varicella.

Twenty-four children with classical chickenpox were referred for ophthalmic assessment because of lesions on the lids and in the eye. The appearance of these lesions, their treatment, and their complications are discussed. Twenty-five percent of these children were documented to have an anterior uveitis.

Anti-Bacterial Agents↗

Brown's syndrome: fusion status and amblyopia.

Many children with Brown's superior oblique tendon sheath syndrome do not have full fusion and stereopsis. Of 28 such patients 8 failed to demonstrate orthophoria in their assumed head position, and many continued to have a head tilt with one or the other eye patched. All eight showed an appropriate vertical deviation, but in addition six showed esotropia and two exotropia. The lack of fusion in their assumed head position led to amblyopia in seven patients.

Amblyopia↗

Self-inflicted ocular injuries in children.

Ocular damage resulting from self-mutilation is not uncommon in severely retarded children. Such injuries are caused by repeated headbanging or self-inflicted blows to the face. We treated four children with self-inflicted ocular injuries ranging from corneal lacerations to vitreous hemorrhage and retinal detachment. One child, a 14-year-old boy with tuberous sclerosis, became blind. Persons caring for such children should be alert to changes in the appearance of the pupil, changes in the personality or performance level of the child, and to the development of exotropia. Early treatment and protective equipment (spectacles or helmets) may prevent permanent injury.

Adolescent↗

Dissociated vertical deviation: associated findings and results of surgical treatment.

The records of 80 consecutive patients with dissociated vertical deviation (DVD) were reviewed. The most frequent initial problem was esotropia, which was noted before 12 months of age in 67 patients. Latent nystagmus was present in 13 patients, and poor stereopsis was documented in 11 of the 29 patients tested. Resection of the inferior rectus muscle, the most frequent surgical procedure in this series, seldom resulted in total resolution of the DVD, but it often yielded cosmetic improvement.

Esotropia↗

Vanishing infantile esotropia.

Three cases of large-angle infantile esotropia are presented. Over a minimum follow-up period of 37 months the angle of esotropia decreased spontaneously to less than 10 prism diopters without surgery or the use of glasses, and recognized late complications of infantile esotropia developed: bilateral overaction of the inferior oblique muscle in three cases, and latent nystagmus and dissociated vertical deviation in two cases each. The significance of these findings is discussed.

Child, Preschool↗

Surgical results in intermittent exotropia.

Among 78 children who had undergone surgery for intermittent exotropia, undercorrection was found in 39, an acceptable result in 33 and overcorrection in 6. A review conducted to determine what factors might explain the high frequency of undercorrection showed that the average age of the patients was higher than usual, and this was a significant prognostic factor. The presence or absence of associated hypertropias, lateral incomitance and A or V patterns was not of prognostic importance. Purposeful overcorrection of the exodeviation by 10 to 15 prism diopters tended to ensure a more satisfactory result.

Adolescent↗