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Biomedical subjects

L Nikolajsen

Publications and source records attributed to L Nikolajsen.

20 records · Page 2Linked to original sources

Sore throat after endotracheal intubation.

Nitrous oxide can diffuse into the cuff of an endotracheal tube during tracheal intubation, and the cuff pressure against the tracheal wall may cause mucosal damage. An endotracheal tube has been developed (Brandt Anesthesia Tube) that effectively limits nitrous oxide-related intracuff pressure increases. We determined whether the incidence of postoperative sore throat could be reduced by using this tube. Forty-eight female patients, 18-50 yr of age, were included in the study. Endotracheal intubation was performed with either a Brandt Anesthesia Tube or a Mallinckrodt endotracheal tube. All patients were interviewed postoperatively after 20-30 h by individuals who did not know which tube was used. In the Mallinckrodt group, 12 of 20 patients had a sore throat and 10 patients had intracuff pressures greater than 25 mm Hg. Only 3 of 20 patients in the Brandt group had a sore throat. We found that the incidence of sore throats after intubation could be significantly reduced by using the Brandt Anesthesia Tube (P less than 0.005).

Adolescent↗

[Capnometry. Technique and clinical use in anesthesia and emergency medicine].

By capnometry is understood measurement of carbon dioxide in the expiratory air. The concentration can be determined by various forms of spectometry. A new acoustic principle of measurement is more sensitive than the methods hitherto employed. Capnometry registers rapid intubation of the oesophagus. Sudden changes in expired carbon dioxide may be signs of malignant hyperthermia or pulmonary embolism. In addition, capnometry is a valuable aid in the regulation of mechanical ventilation. Recent investigations suggest that capnometry can be employed to confirm or refute clinical suspicion of pulmonary embolism and that measurement of expired carbon dioxide may be of prognostic value in resuscitation. It has not yet be elucidated whether nasal measurements in patients who are not intubated can provide reliable values.

Anesthesia↗