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Biomedical subjects

L Mouritsen

Publications and source records attributed to L Mouritsen.

27 records · Page 2Linked to original sources

Inter- and intra-observer variation of colpo-cysto-urethrography diagnoses.

To evaluate the reliability of diagnosing type of bladder suspension defect in incontinent women by means of voiding colpo-cysto-urethrography (CCU), 93 CCU-series with exposures at rest, coughing, withholding and voiding were diagnosed. Three senior and one junior radiologists, a gynecologist and a urologist diagnosed the CCU-series twice with 3-6 months interval. The main diagnostic possibilities were anterior bladder suspension defects, posterior defects and normal, which were in accordance with general practice of choosing an abdominal suspension operation for the anterior suspension defects and a vaginal operation for the posterior defects. The intra-observer agreement varied between 99% and 72%, i.e. 1/5 to 1/4 of the patients changed from one main diagnostic group to another at the two examinations. The inter-observer agreement varied between 43% and 60%. Information of clinical patient data, given to the two clinicians, did not change their CCU-diagnoses significantly. We concluded, that CCU should not be recommended as a routine for evaluation of type of suspension defect since the intra-inter-observer variation was around 25% and 50% respectively. CCU might still be useful preoperatively in selected cases, since it gives an excellent visualisation of bladder base anatomy.

Female↗

Long-term effect of pelvic floor exercises on female urinary incontinence.

In order to assess the permanent effect of pelvic floor exercises on female stress incontinence, 76 incontinent women, referred for incontinence surgery, underwent a 3-month exercise programme conducted by an experienced physiotherapist. The patients were followed up for 1 year. At the last assessment 30% were cured and 17% improved. Altogether 47% avoided surgery. No relapses were seen during the follow-up period. Patients with mild incontinence benefited from intensified training, since 72% could expect to be cured, while patients with severe incontinence and no immediate effect did not benefit from further exercises. Patients with a positive hormone status and those with normal weight had a significantly higher cure rate. The subjective results were confirmed by the 24-h pad test. Anal pressure profilometry was a valid method for instruction and objective control of pelvic floor function. It was concluded that pelvic floor exercises should precede surgery, since exercises had a permanent effect in half of the patients.

Adult↗

The intracavernous injection of papaverine as a diagnostic procedure in patients with erectile dysfunction.

To evaluate the use of papaverine-induced erection as a diagnostic test in men with erectile dysfunction, 24 patients had papaverine injected into the corpus cavernosum. The results of the papaverine test in combination with the tentative diagnosis, based upon patient history, clinical examination and peno-brachial pressure index, gave in most cases sufficient information about the function of the penile vessels to decide in which patients a selective arteriography or a cavernosography was indicated. Two patients developed priapism after the papaverine injection.

Erectile Dysfunction↗

Results of abdominal levator-muscle repair in urinary stress incontinence.

Results of the abdominal levator-muscle repair in 175 stress incontinent women are presented. Two years after the operation 83% were cured or improved regarding urinary incontinence. The urodynamic evaluation revealed a normalization of the maximum flow rate, residual urine and cystometry in nearly all cases. The abdominal levator-muscle repair carried a low morbidity, and is especially recommended in women with combined urinary and anal incontinence.

Abdominal Muscles↗

Renal function following aneurysmectomy of the abdominal aorta.

Postoperative renal function was evaluated in 90 patients operated on for abdominal aortic aneurysms. Forty-four patients were operated on acutely because of impending or actual rupture of the aneurysm. Forty-six patients were operated on electively. The overall mortality rate was 23.7% with a post-operative mortality of 7.8%. Postoperative renal function was evaluated by measurements of the s-creatinine. Impaired renal function was found postoperatively in 45% of the surviving patients. Forty percent of the patients operated on electively had postoperative renal impairment compared with 52% of the patients operated on acutely. The postoperative mortality rate in patients with impaired renal function was 32.4% compared with 8.7% in patients with unchanged renal function. No significant relation between postoperative renal impairment and administration of aminoglycosides, duration of the operation or clamping time of the aorta was found. We found a significant relationship between postoperative renal impairment and episodes of hypotension (p less than 0.01) and the volume of blood transfusions needed (p less than 0.001).

Adult↗