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Biomedical subjects

L Morales

Publications and source records attributed to L Morales.

At least 109 records · Page 6Linked to original sources
PubMed1989

[Biochemical profile of primary hyperparathyroidism. Comparative study with hypercalciuric renal lithiasis].

Primary hyperparathyroidism (PH) is now considered a common condition. Its frequency and the deleterious long-term effects of hypercalcemia make a correct diagnosis mandatory. We attempted to evaluate the usefulness of the indexes of parathyroid function and hormone measurements more commonly used in the diagnosis of PH. To this end we studied 64 patients, distributed in three groups: group with PH, group with hypercalciuric renal lithiasis (HRL) and control group (CG). The results were evaluated with a test of comparison of means and a stepwise discriminating regression analysis. The 8 most useful measurements to differentiate PH from HRL and CG were serum calcium, corrected serum calcium, serum phosphorus, fasting calcium excretion (FCE), maximal tubular calcium reabsorption (MTCR), maximal tubular phosphate reabsorption (MTPR), osteocalcin, PTH half molecule (PTH-HM) and 1,25-dihydroxyvitamin D. The 3-variable and 4-variable groups with a highest discriminating ability were: serum calcium, FCE and PTH-HM, and serum calcium, FCE, PTH-HM and MTPR. We think that the measurement of these four variables is the most adequate strategy for the diagnosis of PH.

Adult↗
PubMed1989

Adrenocortical tumors in childhood: a report of four cases.

In the last 10 years, four children with adrenocortical tumors were treated in our hospital. Three of them had symptoms of adrenogenital virilizing syndrome, and another, nonfunctional, was found during a routine examination. A diagnosis of adrenocortical tumor was established given the symptoms, hormonal tests, and radiologic studies. Two of the tumors were located in the left side, and the histologic diagnosis was pleomorphic cortical adenoma; the ones that affected the right side were adenocarcinomas. All the patients were treated by surgery and none received chemotherapy. At both presurgical and postsurgical stages, the patients were treated with cortisol. All four children have had a favorable course, with normal growth and the disappearance of public hair and hirsutism; however, macrogenitals still persist.

Adenoma↗
PubMed1989

Agenesis of the trachea.

We report a case of agenesis of the trachea type III of Floyd that survived for 2 days with an esophageal intubation. Surgical treatment consisted of a distal esophageal binding, cervical esophagostomy in double-barrelled shotgun, and gastrostomy. Death occurred on the third day after surgery.

Esophagostomy↗
PubMed1989

Segmental dilatation of the duodenum.

In this article two cases of idiopathic duodenal dilation are described. These cases meet the present criteria for segmental dilations of the intestine. The onset of the clinical features was acute in one case and chronic in the other. However, the radiological images were similar in both cases and provided the diagnosis. Surgical treatment consisted of duodenal resection and tapering and was curative in one case. The other patient died shortly after surgery. The duodenal specimens showed normal three-layer duodenal architecture in the pathology study. The intramural nervous plexi were unimpaired. Angiodysplasia was found in one case. Vascular abnormalities were also found in 10 other segmentary intestinal dilatations reported in the literature. The surgical implications of this new localization of segmentary intestinal dilatation are analyzed.

Dilatation, Pathologic↗
PubMed1989

Treatment of an enteric fistula with somatostatin in a premature.

The authors present the case of an extremely premature baby affected by severe Necrotizing Enterocolitis (NEC) needing intestinal resection and ileostomy. An enteric fistula developed 3 days after ostomy closure. The baby was started on Total Parenteral Nutrition (TPN), and 7 days later the fistula output remained constant. Somatostatin (SM) was then given intravenously (3.0 micrograms/Kg/hr) and the fistula closed on the 3rd day of treatment. Since SM was introduced in 1986 as an adjunct treatment to TPN in enteric fistulas, the authors believe that theirs is the first report of a successful SM treatment in a premature.

Enterocolitis, Pseudomembranous↗
PubMed1989

[Usefulness and indications for Port-a-Cath in children with acute leukemia].

Duration of treatment for acute leukemia is as long as 2 years. During this time, venous punctures are repeated every few days. The Port-a-Cath system allows a long-lasting but intermittent venous access. Since March 1987, 11 Port-a-Cath systems have been implanted in 11 children (age 3 to 14) with the diagnosis of high risk acute leukemia (9 ALL and 2 AML). The facial vein has been used in five instances, the external jugular vein in five, and the jugular vein in one case. Ten systems have had a good function. Seven are still in use, and the duration ranges from 450 to 47 days. Two children died because of their disease, their catheters still functioning. Two systems have been withdrawn, one for incorrected location and the other for cutaneous necrosis of the puncture site. Two more children developed reversible thrombosis. The Port-a-Cath system is useful in children affected by high risk acute leukemia, ameliorating their life quality and avoiding the need for repeated vein punctures.

Acute Disease↗
PubMed1989

[Villous adenoma: clinical, endoscopic and histopathologic aspects].

A ten years retrospective study of villous adenomas at the Arzobispo Loayza Hospital was carried out. 24 patients with this problem were found, the mean age was 62 years, clinical symptoms were: rectal bleeding (87.5%), mucus diarrhea (58.2%) and abdominal pain (37.5%). According to the Histopathologic study, there were 14 (58%) adenomas with carcinoma and the existence of carcinoma was proportional to the adenoma's size, we didn't find carcinoma in the adenomas smaller than 2 cm. The endoscopy was useful to detect invasive carcinoma in the 88% of cases meanwhile the endoscopic biopsy detected only 27% of cases. The endoscopic polipectomy was suitable when the adenomas were smaller than 3 cm.

Adenoma↗
PubMed1988

Studies on the microheterogeneity of anterior pituitary follicle-stimulating hormone in the female rat. Isoelectric focusing pattern throughout the estrous cycle.

Anterior pituitary (AP) glands were removed from adult female rats at different times throughout the estrous cycle, and the isohormones of follicle-stimulating hormone (FSH) present within them were separated by isoelectric focusing in polyacrylamide gels (PAGE-IEF; pH range 3.0-8.0). Gel eluents were analyzed for FSH content by radioimmunoassay (RIA) and radioreceptor assay (RRA). All AP samples exhibited several peaks of FSH immunoactivity within a pH range of 6.2-4.0; the major peak constantly exhibited an isoelectric point (pI) of 4.9-4.5. To quantify differences in the IEF pattern of AP-FSH between the pituitaries collected during the different days of the cycle, each PAGE-IEF profile was divided into 7 regions (pI 7.0-6.3 = Area 1, 6.2-5.5 = Area 2, 5.4-5.0 = Area 3, 4.9-4.5 = Area 4, 4.4-4.0 = Area 5, 3.9-3.5 = Area 6, and less than 3.5 = Area 7), and the amount of FSH present within each was determined. In all APs collected at 0900 h of diestrus 1 (D1) and 2 (D2), proestrus (P), and estrus (E); at 1300 h of D1, D2 and E; at 2200 h of P; and at 0200 h of E, the majority of FSH immunoactivity (37-55% of total FSH on gel) focused within Area 4, whereas Areas 2 and 3 contained minor amounts of FSH activity (11-26% and 14-24%, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1988

Iatrogenic arteriovenous fistula in infancy.

Iatrogenic arteriovenous fistulas (AVF) in infancy are rare and are usually located at the level of femoral and antecubital vessels. They are generally secondary to multiple diagnostic or therapeutic arterial or venous punctures. The diagnosis is usually easy to make on clinical grounds; however, invasive procedures such as digital subtraction angiography (DSA) can be used to locate the fistula. These iatrogenic AVF may present as direct vascular communications or pseudoaneurysms originating in the venous wall. Surgical treatment is the therapy of choice. The case of an infant with an iatrogenic AVF of the femoral vessels is presented.

Arteriovenous Fistula↗
PubMed1986

Aesthetic surgery of the supraorbital ridge and forehead structures.

A physical anthropologic basis for aesthetic evaluation of the supraorbital ridges and forehead is described. The structures included for evaluation and possible treatment are the supraorbital ridges, relation of the orbital walls to the eyes, the temporal ridges, and slope of the forehead. All can be altered by reduction contouring or augmentation using methods described. Twenty-one patients are presented having procedures for purely aesthetic reasons. If more than 5 to 6 mm of augmentation or reduction is desired, the deformity is more than aesthetic and should be treated by a craniofacial team. The aesthetic restructuring procedures described are done using tissue localized to the cranium and have proven to be safe and free of complications in the patients treated. Physical anthropology helps to put the aesthetics of these procedures on a firmer basis and to determine which patients may require more than an extracranial aesthetic procedure.

Adolescent↗
PubMed1986

[Pulmonary blastoma at the site of a congenital pulmonary cyst].

Lung blastoma is a rare primary tumor of the lung. There are only 18 cases reported in medical bibliography under 15 years old. A girl 4 years old is reported. A pulmonary congenital cyst in right middle lobe was excised in other hospital at 15 months old. A pneumoblastoma developed at 4 years old in the same location. It was excised by bilobectomy and treated after words with radium and polychemotherapy. Evolution after 29 months of intervention is quite good. She is in good health without recidives or metastases. Lung blastoma is a mixed tumor composed by embryonic mesenchyma and endothelial cores of embryology origin. A review has been done about published cases and it's commented the relation between blastoma and peripheral pulmonary cysts. Three of the 4 cases in pediatric bibliography presented that association and in another the disorders merge with 3 years of influence. In our case the lapse was 31 months after cyst exeresis.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1985

Paraneoplasic precocious puberty. Report of a new case with hepatoblastoma and review of the literature.

A new case of precocious puberty secondary to production of human chorionic gonadotropin (HCG) by an hepatoblastoma was studied in an 8-month-old infant. A review was made of the 35 cases of paraneoplasic precocious puberty previously reported in the literature. The most frequent cause is hepatoblastoma, which was responsible for 18 cases. There are nine reports of mediastinal teratoma, six of which were observed in patients with Klinefelter Syndrome. In another six cases, the paraneoplasic syndrome was attributed to intracranial tumoration, and two of these patients showed teratoma with areas of choriocarcinoma, whereas germinoma was suspected for clinical reasons in another three. Lastly, one case of presacral teratoma and one of retroperitoneal carcinoma were reported. The differential characteristics of paraneoplasic precocious puberty are: almost exclusive occurrence in males, because of tumoral production of HCG, moderate or absent increase of testicle size, hyperplasia of Leydig's cells without spermatogenesis, and rapidly progressive signs of puberty.

Carcinoma, Hepatocellular↗
PubMed1984

[Cervical neuroblastoma in a newborn infant].

A case of cervical neuroblastoma is presented. It was treated by surgical resection followed by homolateral node dissection. No chemotherapy or radiotherapy was done, and patient is free of disease at the present time. We comment on the low incidence of this tumour in newborn and in cervical location, and on the good response of these forms to surgical treatment only.

Head and Neck Neoplasms↗
PubMed1983

Intraspinal migration of a rectal foreign body.

This is a description of a rare case of intraspinal foreign body, a clinical thermometer bulb, which after perforating the rectum migrated through the second left sacral foramina and sacral canal up to the epidural space at S1-L5 level. A first attempt to remove it by laparotomy while it was still in the retrorectal space proved unsuccessful. Retrieval was finally achieved by laminectomy.

Child, Preschool↗
PubMed1983

[Results and complications of CSF shunting in hydrocephalus].

Fifty four patients with hydrocephalus treated with surgical derivations were evaluated in retrospect. The total number of derivations made to this group was 76. Initially 30 valves were from VA type and the remaining 24 from VP type, but reintervention was needed in 15 and 11 respectively. The etiology of hydrocephalus was congenital in 61%; infectious, in 24%; tumoral, in 8%, and consequence of a traumatism, in 7%. Twenty-three patients (42%) followed a good evolution without any complication as much immediately as later. The other 31 patients (57%) have had some kind of postoperative complication. In 26 patients (48%) the valve had to be removed. The main causes were infection in 10 cases (18%) and obstruction in 14 cases (25%). Usually the staphylococcus was the infectious agent. Ten of the patients died (18%), eight of them by a complication directly related to the shunt.

Anti-Bacterial Agents↗