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Biomedical subjects

L Michel

Publications and source records attributed to L Michel.

At least 127 records · Page 7Linked to original sources
PubMed1979

Tracheostomy and indwelling central venous line: a hazaradous combination?

A prospective study of 390 indwelling central venous catheters placed via the subclavian route defined bacteremia and tracheostomy as the only significant variables associated with the colonization of the catheters by pathogenic microorganisms. Catheter related sepsis was likely in only 3 of 33 episodes of proven bacteremia. Detailed statistical analyses of other potential contaminating factors revealed no significance. Specific concern must be assigned to placement of central venous catheters by the subclavian approach, when a tracheostomy is already present,

Bacterial Infections↗
PubMed1979

Guide wire-sheath technique for pulmonary artery catheterization and central vein cannulation.

The combination of a spring guide wire with a sheath introducer system has been successfully used for the routine placement of pulmonary artery and central venous catheters. The method, which is described is simple, quick, and safe. It is applicable to the initial placement of the catheter, to any necessary alterations in its position, and to its eventual replacement with a central venous cannula.

Cardiac Catheterization↗
PubMed1979

Microbial colonization of indwelling central venous catheters: statistical evaluation of potential contaminating factors.

A prospective study of 390 indwelling central venous catheters placed by way of the subclavian route identified bacteremia and tracheostomy as the only significant variables associated with the colonization of the catheters by pathogenic microorganisms. Catheter-related sepsis was likely in only 3 of 33 episodes of proved bacteremia. Detailed statistical analyses of other potential contaminating factors revealed no significant correlations.

Bacteria↗
PubMed1979

Measurement of ventilatory reserve as an indicator for early extubation after cardiac operation.

The decision to perform tracheal extubation in 44 patients who underwent cardiac operation was based on an assessment of mental alertness, recovery of muscle strength, hemodynamic stability, and adequacy of pulmonary gas exchange. No patients required reintubation. Concomitant measurements of vital capacity (VC) and maximal inspiratory pressure (PImax) were made before a trial of spontaneous ventilation was commenced, after 45 minutes of spontaneous ventilation, and after tracheal extubation. By generally accepted criteria, these measurements suggested the need for continuing mechanical ventilation in 14 patients at the time mechanical ventilatory support was removed and in eight patients at the time of tracheal extubation. In this study, consideration of measurements of VC and PImax would have led to longer trachael intubation, especially in those patients who were extubated within 10 hours of the completion of anesthesia.

Anesthesia, General↗
PubMed1978

Knotting of central venous catheters: nonsurgical correction.

A complete knot occurred in a central venous catheter inserted through the subclavian vein. By passing a spring guidewire into the catheter under fluoroscopic control, the knot was easily untied leaving the catheter correctly in place.

Cardiac Catheterization↗
PubMed1978

[Draining of radioactive waste water from departments working with radioactive material after introduction of the law for radiation protection (author's transl)].

In order to establish the drainage of radioactive waste water 1976 in the Federal Republic of Germany a new law for radiation protection was introduced. In this paper a concept is introduced how to determine specifications for constructing a decay plant using the given data of a department for nuclear medicine. The given boundary conditions were to secure a low concentration of radioactive material in order to establish the drainage of extreme low activities without diluting it.

Berlin↗
PubMed1976

Post-column fluorescence derivatization of peptides. Problems and potential in high-performance liquid chromatography.

Some critical parameters such as the pumping system, mixing devices and detector design in instrumentation for post-column derivatization in high-performance liquid chromatography are discussed. The derivatization was studied with pharmaceutically important nona-peptides containing primary amino groups which react with Fluram and reaction parameters such as pH, solvent and reagent concentration were investigated. Both adsorption systems and reversed-phase systems were used to separate the peptides prior to the post-column reaction. Reversed-phase chromatography has the advantage of simpler sample preparation, better reaction control and optimization of solvent conditions. As a result, detection limits of between 5 and 10 ng per injection can be obtained and the reproducibility of the results is better than +/- 2% (relative standard deviation). The method has been applied to the analysis of injection solutions (ampoules).

Amino Acid Sequence↗
PubMed1976

[A simple method for evaluation of the lecithin/sphingomyelin ratio in amniotic fluid. Variation in normal and abnormal pregnancies (138 cases) (author's transl)].

The determination of the lecithin/sphingomyelin ratio in amniotic fluid is a useful index for assessing fetal pulmonary maturity. The authors propose a simple and specific method : the amniotic lipids are extracted and thin layer chromatography is carried out in an acetic acid containing medium. The L/S ratio was studied and discussed in 138 normal and pathological cases.

Amniotic Fluid↗
PubMed1975

[Severe complications of subclavian vein catheterization].

The authors report 4 observations of severe involvement induced by sub-clavian catheterization: - 2 catheter-embolisms; - 1 venous thrombosis and one hydrothoraxx. One embolism and the hydrothorax were caused by a faulty puncturing. The thrombosis was the result of a relative stenosis of the vein induced by a loop of the catheter in the Pirogoff confluent. Next, the authors develop the facts given by the literature bearing upon each one of these complications.

Catheterization↗