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Biomedical subjects

L McDonnell

Publications and source records attributed to L McDonnell.

28 records · Page 2Linked to original sources
PubMed1983

Music therapy: meeting the psychosocial needs of hospitalized children.

Music therapy offers a unique approach for reducing the stresses of hospitalization for children. By meeting important psychosocial needs, music therapy lessens anxiety, aids adaptation and contributes to making the hospital experience a more positive one. The use of music therapy is described and illustrated with three patients all of whom underwent painful and prolonged hospitalization with immobilization and severe movement restriction.

Child↗
PubMed1982

Studies on nuclear estradiol receptors in human mammary carcinomas.

Nuclear estradiol receptors (NER) were measured in human breast carcinomas by extracting nuclei with 0.6 mol/l KCl and adsorption to hydroxylapatite. NER were found in 34/58 tumors containing cytoplasmic estradiol receptors (CER) and in only 8/34 tumours without CER. NER correlated with CER but not with cytosol total estrogens or progesterone. NER levels also showed no significant correlation with either tumor stage, grade, cellularity, size, or presence or absence of axillary node metastases.

Breast Neoplasms↗
PubMed1981

Medullary carcinoma of the thyroid presenting as tumours of the pharynx and larynx.

Two cases of medullary carcinoma of the thyroid presenting as tumours of the pharynx and larynx are described. One patient had a tonsillar mass that resembled a carotid body tumour clinically, radiologically and microscopically. The other had an arytenoid tumour with multiple cervical lymph node metastases but without intrathyroidal carcinoma. The endocrine nature of the neoplasms was indicated by the presence of stromal amyloid, cellular argyrophilia and secretory granules whilst the demonstration of calcitonin and carcinoembryonic antigen provided evidence that they were medullary carcinomas.

Aged↗
PubMed1981

Lung scar cancer--a reappraisal.

A retrospective clinicopathological study of 100 necropsy cases of lung carcinoma revealed three scar cancers. The scarring in a further 11 probably occurred secondary to the tumour. The premise that lung scars initiate malignancy is questioned.

Adenocarcinoma↗
PubMedDate not supplied

A non-contact mode scanning force microscope optimised to image biological samples in liquid.

Given that biological samples are particularly soft in their natural state and that a liquid is the most difficult operating environment for non-contact mode scanning force microscopy, the development of a scanning force microscope that is optimised to image biological samples in vitro presents significant challenges. The performance of the instrument described here has been optimised for such an application by incorporating magnetic excitation and active-Q control of the cantilever. The application of this instrument has been validated by imaging monolayers of immobilised antibodies in liquid and achieving image qualities comparable to those achieved in air for such samples.

Antibodies, Monoclonal↗