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Biomedical subjects

L Marsk

Publications and source records attributed to L Marsk.

27 records · Page 2Linked to original sources
PubMed1977

Developmental precocity after asynchronous egg transfer in mice.

Asynchronously transferred ova were found to implant 6-8 h earlier than did non-transferred eggs, indicating that the endometrium was receptive to implantation several hours before the native blastocysts were prepared to implant. This developmental precocity was also preserved on day 14, according to the results of a morphological rating study on day 14. Synchronously transferred ova showed no such developmental precocity. No statistically significant difference in implantation time or development on day 14 was found between the two strains, CBA and A/Jax. The importance of precocious development for planning teratological studies is emphasized.

Animals↗
PubMed1975

Developmental precocity in transferred mouse embryos influencing the teratogen response to salicylate.

Asynchronous blastocyst transfer, supposed to equalize the developmental stage of native and alien embryos during the organogenic period, was used as a tool in a teratological investigation. A spurious protection by the transfer as such was shown to depend on a persisting asynchrony between native and alien foetuses. The initial difference of 24 h was not nullified, but decreased to 8 h. This difference allowed transferred foetuses to pass the period of maximum sensitivity before salicylate treatment.

Abnormalities, Drug-Induced↗
PubMedDate not supplied

Prenatal diagnosis of chondroectodermal dysplasia with fetoscopy.

Chondroectodermal dysplasia (Ellis-van Creveld syndrome) has previously been diagnosed prenatally only once, using fetoscopy. We report on two consecutive pregnancies in a woman at risk of having a child with the syndrome during which fetoscopic visualization was performed. Ellis-van Creveld syndrome was diagnosed prenatally in one instance, while it could be excluded in the other one. Non-invasive prenatal diagnosis of the syndrome is discussed.

Adult↗