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Biomedical subjects

L Mancini

Publications and source records attributed to L Mancini.

93 records · Page 6Linked to original sources

Charcot's foot.

Diabetic osteoarthropathy is a chronic progressive arthropathy involving the bones and joints being constantly associated to somatic and autonomic peripheral neuropathy. The pathogenesis is related to sensory and motor neuropathy with morphologic foot alterations, relaxation and abnormal position on walking till complete collapse of the foot shown by the depressed longitudinal medial arch. Bone reabsorption due to osteoclasis and increased blood flow until osteomalacia appears, is characteristic of this arthropathy. The clinical features vary according to the location and severity of articular impairment and the stage of identification. The metatarsophalangeal or tarsometatarsal joint may be involved. The typical manifestation of Charcot's foot is plantar ulcer of variable location according to the weight-bearing area. Treatment tends to reduce the abnormal stress predisposing to ulceration with tailored footwear and orthoses.

Adult↗

Infection of the diabetic foot.

Infection may be the first manifestation of the diabetic foot or may complicate a preexisting lesion. The increased susceptibility to infections of diabetics and the particular anatomy of the foot make infections particularly severe and rapidly progressive. The etiology is generally polymicrobial and a swab for culture of microorganisms is immediately required to plan correct and adequate antibiotic therapy based on the antibiotic sensitivity test. Infections can be treated in specialized outpatient services, while hospitalization is reserved to most severe cases with systemic manifestations. These specialized centers have been shown to be the only structures able to decrease the frequency, severity and recurrence of foot infections as well as their prevention.

Bacterial Infections↗

The foot clinic. Multidisciplinary management of the patient with diabetic foot.

Treatment of a complex disease as the diabetic foot requires a multidisciplinary management with the close collaboration of a team for care. The most important members of the team are the diabetologist as coordinator, the vascular surgeon, the orthopedist, the radiologist, the orthopedic technician, the podiatrist and the nurse specialist. The care based on this arrangement should be carried out in dedicated rooms and times to exploit at best the organizational potential in the patient's interest, implemented in the foot clinic.

Diabetic Foot↗