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Biomedical subjects

L M Zhang

Publications and source records attributed to L M Zhang.

86 records · Page 5Linked to original sources
PubMed1988

Analysis of the causes of maternal death in China.

Data were analysed on maternal mortality for 1984 in 287 cities, districts, and counties in 21 provinces, municipalities, and autonomous regions of China. The total population covered was 177.55 million, and during the study period there were 2 483 269 live births and 1211 maternal deaths, corresponding to a maternal mortality rate of 48.8 per 100 000. The main cause of maternal death was obstetric haemorrhage, followed, in order, by cardiac diseases, toxaemia of pregnancy, hepatic disease, puerperal infection, and amniotic fluid embolism. The health care measures received by the mothers who died are analysed, and methods of reducing the maternal mortality rate are proposed.

Cause of Death↗
PubMed1987

Dextrorphan: an antagonist for phencyclidine receptors.

Radio-binding assay, bioassay and HPLC detection were used to observe the antagonistic effects of dextrorphan on PCP's actions. Dextrorphan displayed high affinity to PCP receptor in the rabbit mesenteric blood vessels. It had weak PCP-like bioactivity, but could antagonize PCP's action dose-dependently in vitro study with the rabbit ear artery preparation and shifted the dose-response curve of PCP to the right. After PCP administration, the content of norepinephrine in the vascular bath medium was increased, which was reversed by dextrorphan. Thus suggests that dextrorphan is an antagonist with very mild agonistic action for PCP receptors.

Animals↗
PubMed1986

Dextrorphan: an antagonist for phencyclidine receptor.

Radio-binding assay, bioassay and HPLC detection were used to observe the antagonistic effects of dextrorphan on PCP's actions. Dextrorphan displayed high affinity to PCP receptors and it had weak PCP-like bioactivity, but could antagonize PCP's action dose-dependently in vitro and shift the dose-response curve to the right. PCP increased the contents of norepinephrine in bath medium, which was reversed by dextrorphan. Thus, the results suggest that dextrorphan is a partial antagonist for PCP receptors.

Animals↗