[Sclerosing hemangioma of the lungs].
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Biomedical subjects
Publications and source records attributed to L M Krylov.
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Electron microscopic study of leiomyoma of skin arteries, oesophagus leiomyoma, leiomyosarcoma and rhabdomyosarcoma was carried out. In the tumor cells myofilaments were found sometimes forming hexagonally packed myofibrilles, formations resembling desmosomes. This permitted the establishment of valid myogenic histogenesis of these neoplasias.
The paper describes 12 cases of spindle cell thymoma without myasthenia or any other syndromes such as hypogammaglobulinemia, hypoplasia of the red sprout of the bone marrow. In most patients the tumours were detected roentgenologically. Microscopic diagnosis of spindle cell thymoma is based on the detection in it of epithelial cell structures. In those cases where the tumours were represented by spindle cells alone, verification of the tumor was possible only by electron microscopic studies (the presence in the cells of tonofilaments, desmosomes and basal membrane).
An electron-microscopy investigation of two fibrosarcomas was carried out. Blastomatous elements were represented by fibroblasto-like cells. In their cytoplasm there were observed phaged fragment of collagenic fibrils, and in small canals of the granular endoplasmic reticulum--crystalloid formations. Diagnostic significance of these findings is discussed.
Electron microscopic examinations of two malignant fibroxanthomas revealed some ultrastructural features characteristic of this tumor. The tumor elements were represented by histiocyte-like, fibroblast-like and little differentiated cells. In some of the latter the signs of macrophage differentiation could be seen and therefore a possibility of their transformation into histiocytes is assumed.
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It is shown that changes in the vessels of the central nervous system, neurons and interneuron links--synapses develop in AEP. Increasing diffuse-focal destructive brain changes are morphological substrate of toxico-hypoxic encephalopathy and basis for disturbances of an integrative-trigger action of the brain.
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