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Biomedical subjects

L M Klevay

Publications and source records attributed to L M Klevay.

At least 109 records · Page 6Linked to original sources
PubMed1976

The biotin requirement of rats fed 20% egg white.

The biotin requirement of rats fed a diet based upon 62.4% sucrose, 20.0% egg white and 10.0% corn oil was determined using growth for 60 days as the cirterion. Maximal growth and maximal concentration of cholesterol in plasma occurred when the diet contained 2.00 mg biotin/kg. Growth depression was noted in one of two experiments in which 3.00 mg of biotin was present per kg of diet.

Animals↗
PubMed1976

Hypercholesterolemia due to ascorbic acid.

Rats fed a purified diet containing ascorbic acid developed hypercholesterolemia. Because rats do not require exogenous ascorbic acid, they may be comparable to humans who supplement their diets with ascorbic acid in capsular form. The amount of ascorbic acid in this experiment was equivalent to 82 to 630 mg of capsular ascorbic acid ingested by an average man and was well below the amount ingested by those in search of respiratory benefit. The data are consonant with those on humans consuming controlled diets.

Animals↗
PubMed1975

Coronary heart disease: the zinc/copper hypothesis.

Epidemiologic and metabolic data are consanant with the hypothesis thata metabolic imbalance in regard to zinc and copper ia a major factor in the etiology of coronary heart disease. This metabolic imbalance is either a relative or an absoulte deficincey of copper characterized by a high ratio of zinc to copper. The imbalance results in hypercholesterolemia and increased mortaility die to coronary heart disease. The imbalance can occur due to the amounts of zince and copper in human food, to lack of protective substances in food or drinking water and to alterations in physiological status that produce adverse changes in the distribution of zinc and copper in certain important organs. Because no other agent, with the possible exception of cholesterol, has been related so closely to tisk, the ratio of zinc to copper may be the preponderant factor in the etiology of coronary heart disease.

Adolescent↗