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Biomedical subjects

L Love

Publications and source records attributed to L Love.

At least 37 records · Page 2Linked to original sources

Computerized tomography scan in the preoperative staging of renal cell carcinoma.

Forty-two patients with renal cell carcinoma were evaluated with computerized tomography (CT) followed by surgical exploration, extirpative surgery, or autopsy to determine the accuracy of the CT scan in assessing the extension of the disease. There was an overall accuracy of 95 percent (40/42 patients). The two staging errors were misinterpretation of renal vein involvement and liver invasion. The CT scan is an accurate preoperative indicator of the diagnosis, state, and extension of renal cell carcinoma. Other radiologic studies (arteriography and inferior venacavography) should be used as complementary studies in selective patients.

Carcinoma, Renal Cell↗

Normal excretory urography in patients with primary kidney neoplasms.

The records of 65 consecutive patients discharged from the hospital with a diagnosis of primary parenchymal neoplasm of the kidney were reviewed. Four of the 65 patients had neoplasms which were not detected by excretory urography. The 4 undetected lesions included 3 renal cell carcinomas and 1 oncocytoma. All of these lesions projected from the anterior or posterior surface of the kidney, and all 4 were clearly demonstrated by computed tomography. Normal findings on an excretory urogram do not completely exclude a neoplasm of the kidney. When there is strong clinical suspicion of a renal neoplasm, computed tomography should be the initial examination or should be done even if the urogram has shown normal findings.

Adenoma↗

Dynamic components of nasal resistance.

This investigation was undertaken to demonstrate the contributions of dynamic vestibular and mucosal components to nasal air-flow resistance in healthy human adults. The studies were made by video recording of alar movement, electromyography of alar muscle activity, and by computer-assisted plethysmographic measurement of nasal air-flow resistance. Inspiratory approximation of the alae toward the septum from their expiratory position averaged only 0.6 mm at the high nasal ventilation of 35 L/min; it was less at lower ventilation and absent during voluntary mouth breathing. Inspiratory electromyographic activity also was directly related to the extent of nasal ventilation and was absent during voluntary mouth breathing. The activity was consistent with phasic muscular restraint of vestibular compliance with inspiratory transnasal pressures. Physiologic nasal air-flow resistance changes associated with posture, the nasal cycle, exercise, and hyperventilation persisted despite immobilization of the alae by splinting the vestibule widely open. These changes were abolished by topical decongestant, even in the unsplinted nose, and are therefore vascular.

Adult↗

Computed tomography of internally calcified renal cysts.

Three benign renal cysts containing nonperipheral calcifications on CT are presented. Renal cyst puncture and cytologic examination of the aspirate confirmed their benign nature. Calcification, either peripheral or within the mass, may occur in benign or malignant cystic lesions of the kidney. The demonstration of calcification is a definite indication for cyst puncture to avoid unnecessary surgery or overlooking a possible malignancy.

Calcinosis↗

Evaluation of superior vena cava syndrome by axial CT and CT phlebography.

Transverse axial computed tomography (CT) has been combined with CT digital phlebography to study nine patients with superior vena cava syndrome. Six were due to malignancy, two were secondary to benign disease, and one was a paraneoplastic manifestation. This combined CT approach successfully identified the abnormal morphology of the superior vena cava, demonstrating external compression, encasement, or intraluminal thrombus in all patients and the collateral venous channels in eight. The efficacy and advantages of this technique are discussed. This technique is a rapid, informative, and cost-effective method for the workup of superior vena cava syndrome. The CT digital phlebogram, however, is not successful in regularly and optimally opacifying the normal superior vena cava because of the limited amount of contrast material, dilution effect of the nonopacified incoming flow from the jugular and azygos veins, and the lack of image enhancement from the CT digital scanograms.

Adenocarcinoma↗

Intravenous contrast bolus in computed tomography investigation of mass lesion.

Using bolus intravenous contrast (25-75 Renografin 60) and 5-second scanning capability, better definition of vascular anatomy as well as the vascular nature of mass lesions in the chest and abdomen could be demonstrated. The immediate higher concentration of iodine in vessels and organs following initial bolus, improves visualization of these structures dramatically when compared to drip-infusion technique. A description of the technique and examples are shown.

Abdominal Neoplasms↗

The rim nephrogram in renovascular compromise.

The nephrogram is a sensitive indicator of renovascular compromise. An infrequently reported but characteristic nephrographic abnormality is the cortical rim nephrogram. This "rim sign" refers to a thin nephrographic rim outlining a kidney with an otherwise faint nephrogram. We report 2 patients with this nephrographic appearance due to acute renal artery insult. The rim nephrogram is a reliable sign of underperfusion of the kidney. It is dependent on collateral capsular vessels supplying the outer renal cortex. Underperfusion can be due to a primary renal artery problem or secondary to compromise of renal artery perfusion because of elevated interstitial or tubular pressure in the kidney. The sign has not been described with systemic circulatory problems.

Adult↗

Diagnosis of dissecting aortic aneurysm by computed tomography.

Computed tomography (CT) of the torso combined with simultaneous intravenous bolus injection of contrast media was used in sixteen patients suspected of having dissected their aorta. All patients had subsequent correlative percutaneous aortography within 24 h of the CT examination. Four patients proved to be normal, one had an aneurysm of the thoracic aorta, and eleven had aortic dissection (five type I, six type III dissection). All eleven patients with aortic dissections were diagnosed by CT and angiography; nine had spontaneous dissections and two had iatrogenic injuries to the aorta. Limitations of this imaging procedure include; inability to detect aortic valvular dysfunction and failure to provide an adequate perspective of aortic branch involvement. Potential benefits include: avoidance of aortogram in some cases, relative non-invasiveness, rapidity and ease of procedure, and less expense, radiation, contrast media, and discomfort to the patient. Early experience with CT-enhancement technique has reliably demonstrated normal as well as abnormal aortic wall morphology. It may have a place as an alternative to the conventional aortogram.

Adult↗

Pancreatic tumor imaging by III generation CT, gray-scale ultrasound and improved angiography.

Thanks to computed tomography (CT) and gray-scale ultrasounds the possibilities of morphological diagnosis in pancreatic disease have improved. Nevertheless, only a part of the potential performances of this practice is known and especially for ultrasounds, where only an expert eye can properly read the resulting images. With the help of pictures we hereby deal with the above-mentioned procedures in the demonstration of a pancreatic neoplasm. The possible integration with other more invasive methods was verified compared to pancreatic angiography. The latter is irreplaceable in the presurgical stage, and the method proposed by the authors can be useful when other methods cannot be employed.

Angiography↗