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Biomedical subjects

L Liss

Publications and source records attributed to L Liss.

At least 37 records · Page 2Linked to original sources
PubMed1975

Diffuse reticulosis with leukomalacia.

A malignant lymphoproliferative disease with acute clinical course and selective clinical CNS involvement is described. The metastatic lesions in the brain are compared with a primary microglioma of the brain.

Blood Vessels↗
PubMed1975

Astrocytic processes: A route between vessels and neurons followingblood-brain barrier injurt.

The fluorescent tracer Evans blue (EB) was studied after circulation time ranging from 30 seconds to 5 minutes following blood-brain barrier (BBB) injuries in 42 dogs. Selective neuronal stainings (sns), associated with BBB injuries, occurred to a high degree. This phenomenon was examined by modifications in existing fluorescence techniques. The mechanism of SNS was seen to lie in an almost imperceptible transport of EB along astrocytic processes connecting SNS with the adjacent vasculature. This report presents visual evidence under pathological conditions, and supports the concept of astrocytic processes as the normal route of transport between blood vessels and neurons. This requires long exposure photomicrographs since the fluorescing material is subtle within the neuroglial processes.

Animals↗
PubMed1975

Tumor-specific transplantation immunity to intracerebral challenge with cells from a methylnitrosourea- induced brain tumor.

Tumor-specific transplantation immunity was demonstrated in syngenic rats immunized and challenged with tumor cells (T9) from an N-methyl N-nitrosourea-induced brain tumor. All unimmunized rats and rats pretreated with normal glial cells in complete Freund's adjuvant or with adjuvant alone died of intracerebral (i.c.) neoplasia at approximately 3 weeks post-challenge. Rats which were immunized with T9 cells with or without adjuvant failed to develop i.c. tumors by 6 weeks even though the challenge dose was 2 logs greater than a dose which consistently resulted in neoplasia in unimmunized rats.

Animals↗