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Biomedical subjects

L Lindberg

Publications and source records attributed to L Lindberg.

99 records · Page 6Linked to original sources
PubMedDate not supplied

Trends in the relationship between breastfeeding and postpartum employment in the United States.

It is widely assumed that employment and breastfeeding are relatively incompatible behaviors in the United States; yet recently both the incidence of breastfeeding and the incidence of postpartum employment increased. This paper examines the relationship between these trends from 1968-86 using data from the National Surveys of Family Growth. I find that these trends result from increases in the likelihood that a woman engages in both breastfeeding and postpartum employment. There has been an increase over time in the incidence and duration of women concurrently breastfeeding and working. However, the majority of employed women did not concurrently breastfeed, suggesting that conflicts between these behaviors still exist.

Adolescent↗
PubMedDate not supplied

Nondisplaced and minimally displaced fractures of the lateral humeral condyle in children: a prospective radiographic investigation of fracture stability.

Subsequent displacement of nondisplaced or minimally displaced fractures of the lateral humeral condyle while immobilized in plaster may contribute to severe complications. The possibility of assessing the stability of such fractures may be a help in planning the initial treatment. Our prospective investigation of 112 children aged 1-11 years aimed at describing radiographic criteria for prognosticating the stability of the fractures. According to the radiographic findings, the fractures were allocated to one of three groups representing stable fractures, fractures with undefinable risk, and fractures with high risk of later displacement. All children were treated with splinting only. Sixty-five fractures were classified as stable and turned out to be so without exception. Displacement occurred in six of 35 (17%) of the fractures judged uncertain and in five of 12 (42%) of those judged unstable. The subsequent displacement was 1 or 2 mm, and in one case, 3 mm. The defined criteria were found to be efficient in separating the stable and the high-risk fractures with acceptable confidence. The group of fractures with undecided risk of subsequent displacement was fairly large--one third of the total material. The implication the findings may bear to the treatment strategy of fractures is analyzed in a work in progress.

Child↗
PubMedDate not supplied

Effect of cortical perforations of both graft and host bed on onlay incorporation to the rat skull.

The mechanisms involved in the integration of autogeneic bone grafts still attract much interest due to their clinical importance. The purpose of this study was to obtain data on the effects of a combination of cortical bone perforations both at the recipient site and the inner layer of a bicortical graft. 12 adult rats obtained femoral or tibial bicortical bone grafts from isogeneic donors to the tibia, one on each leg. On the experimental side, both the recipient bed and the inner cortical graft layer received multiple perforations (0.25 mm in diameter), while on the control side, only perforations of the recipient cortical bed were made. The findings were assessed by routine histology and immunohistochemical analysis for some bone and cartilage matrix proteins after 4 and 20 weeks. The combined cortical perforations of the graft and the host bed induced a locally improved bony incorporation of the graft and a corticalization of the graft marrow, implying improved mechanical stability. The graft height persistence was similar between groups. Intense labelling of the bone matrix proteins was apparent in all bone tissue and by diversified intensity at its various components, demonstrating ongoing remodeling activities. PRELP and fibromodulin mainly outlined the soft tissues surrounding the graft and compact bone sealing off the graft marrow. Immunolabelling contributed a more delicate picture of the mechanisms involved in graft incorporation.

Animals↗
PubMedDate not supplied

Temperature control and light penetration in a feedback interstitial laser thermotherapy system.

The aim of this study was to describe the performance of a closed loop interstitial laser thermotherapy system in processed liver and to demonstrate its suitability for treating a vascularized tumour in vivo. The thermotherapy system consisted of an Nd: YAG laser and a temperature feedback circuit including an automatic thermometry system and thermistor probes. Experiments in processed liver were performed with a sapphire probe and temperature control at a distance of 10 mm. In most experiments at 1-2 W, and in half of the experiments at 3 W, there was no carbonization, a moderate change in the light penetration and excellent control of the temperature. In experiments with output powers of 4-5 W there was carbonization with rapid deterioration of light penetration and impaired control of the temperature. Carbonization affected the distribution of temperatures, which were lower below, and higher above, the laser tip in experiments with carbonization as compared to experiments without carbonization. Treatment of an adenocarcinoma implanted into rat liver was performed at 2 W with a bare fibre and without blood inflow occlusion. The feedback thermistor probe was placed 3 mm outside the margin of the tumour (largest diameter 9.5 +/- 0.3 mm (mean +/- SEM)). Temperature control and light penetration characteristics were similar to those found in vitro. No tumour could be demonstrated at sacrifice 6 days later. It is concluded that a closed loop feedback system can produce stable and reproducible local hyperthermia, that it performs better when carbonization is avoided and light penetration is preserved and that it has a great potential for interstitial thermotherapy of malignant tumours.

Animals↗
PubMedDate not supplied

Aerobic and anaerobic bacteria in deep infections after total hip arthroplasty: differential diagnosis between infectious and non-infectious loosening.

Five separate biopsy samples for bacterial culture were taken at primary total hip arthroplasty in patients without signs of infection and at reoperation of patients with infectious and noninfectious loosening of the prosthesis. Based on the results of the culture, on serologic results and on the erythrocyte sedimentation rate, bacteria of clinical significance could be distinguished from contaminants. Growth in one or two of five biopsy samples was a strong indicator of contamination, while growth in five of five biopsy samples of one or two bacterial species strongly indicated an infection. These diagnostic procedures are applied to differentiate between infectious and noninfectious loosening of the prosthesis. In the delayed infections, the low-virulent aerobic and anaerobic bacteria Staphylococcus epidermidis, Propionibacterium acnes and peptococci were predominant.

Antibodies, Bacterial↗
PubMedDate not supplied

Hematogenous infection in total joint replacement.

Hematogenous infections may appear at any time after joint replacement operations. As distinguished from delayed infections where general symptoms of infection are absent, hematogenous infections cause malaise, chills and fever, usually of the septic type. Roentgenograms of the joint at an early stage of hematogenous infection do not show any sign of infection as these take time to develop. Nor is the scintigram positive at an early stage. The diagnosis is beyond doubt only when the same strain of bacteria is cultured from the joint, a primary focus and blood.

Adult↗