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Biomedical subjects

L Levy

Publications and source records attributed to L Levy.

At least 307 records · Page 17Linked to original sources
PubMedDate not supplied

Importance of the footpad lesion in the mouse response to local inoculation of Mycobacterium marinum.

The importance of the footpad lesion was studied in CBA mice inoculated in the hind footpad with viable or heat-killed Mycobacterium marinum Popliteal or popliteal and inguinal lymphadenectomy was followed by modest enhancement of the process only when node excision was carried out 6 days after inoculation of a small number of viable organisms. Following inoculation in the footpad of a large number of heat-killed organisms, only 10% of the inoculum was recovered from the site of inoculation, only 0.1% from the popliteal node and even less from the inguinal node and spleen. Despite the small proportion of inoculated M. marinum remaining in the footpad, amputation of the inoculated foot as early as 4 days after inoculation abrogated the protective effects of the inoculation, whereas amputation performed 7 days after inoculation was without effect.

Amputation, Surgical↗
PubMedDate not supplied

Using a trade-off technique to assess patients' treatment preferences for benign prostatic hyperplasia.

The probability-tradeoff technique may be used to assess treatment preferences in dichotomous choices. In this feasibility study, it was used to elicit benign prostatic hyperplasia (BPH) patients' attitudes towards three different treatments. Eighty-seven male outpatients used rating scales and the standard gamble to indicate the extents to which they were free of BPH symptoms. Paired descriptions of "watchful waiting" (WW), treatment with an alpha blocker (AB), and transurethral resection of the prostate (TURP) were presented, and the probability-tradeoff technique was used to obtain treatment-preference scores. The tradeoff task identified six internally consistent preference-order subgroups. The majority (n = 55; 63.2%) were in the two subgroups in which TURP was the least-preferred treatment. Compared with the other respondents, the members of these two subgroups reported significantly higher utilities for their BPH symptom status (89 vs 79; t = 2.87; p < 0.0005). Within each subgroup, preference scores for the middle- and top-ranked treatments were computed relative to the bottom-ranked treatment; for both WW and AB, significant across-subgroup differences were observed. In this preliminary study the probability-tradeoff technique was feasible, able to identify unique preference-order subgroups, and able to generate apparently meaningful preference scores in a clinical situation involving three alternative treatments. Further development of tradeoff tasks as the value-clarification component of decision aids for individual patients seems warranted.

Aged↗
PubMedDate not supplied

How well do consumers understand percentage daily value on food labels?

One hundred four adults completed a multiple choice food label comprehension questionnaire and a food frequency questionnaire. Most respondents were able to accurately rate the fat content of five different foods using only the food label information. However, some underestimated food content for some foods. Also, only 29% correctly selected the definition of % daily value for fat (%DV), as "percent of the maximum daily recommended amount of fat."

Adult↗
PubMedDate not supplied

[European multicenter cross-sectional study on exposure to low doses of benzene].

A cross-sectional multicenter european study has been carried out to evacuate the relations between exposure to low level of benzene and biological markers of internal dose (t,t-MA, S-PMA) and early biological effect (DNA-SSB). The research has shown significantly increased levels (adjusted for smoking habits) of the urinary excretion of t,t-MA, S-PMA and DNA-SSB in petrochemical workers (mean benzene level = 5,694 micrograms/m3) but not in filling station attendants, traffic police officers, and bus drivers compared to referent workers. Dose-response relations were detected between benzene air levels, t,t-MA, S-PMA and DNA-SSB in petrochemical workers, with significantly increased levels of DNA-SSB detected for benzene exposure levels in the range 391-1,800 micrograms/m3 (0.12-0.58 ppm).

Benzene↗
PubMedDate not supplied

Rejoinder.

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Animals↗
PubMedDate not supplied

[Amine oxidases].

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Amphetamine↗