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Biomedical subjects

L Lawson

Publications and source records attributed to L Lawson.

61 records · Page 4Linked to original sources

Milieu management of traumatized youngsters.

TOPIC: Traumatized youngsters are disproportionately represented in out-of-home treatment facilities. Conceptual models that guide treatment of traumatized youngsters are not well integrated with models that guide milieu management. PURPOSE: To describe a milieu management approach for treatment of traumatized youngsters. SOURCES: Clinical experience with hospital and residential treatment facilities and therapeutic foster homes, as well as literature support. CONCLUSIONS: Familiar treatment strategies take on an additional meaning when they are implemented in the context of the children's histories of exposure to traumatic events.

Child↗

Preparing sexually abused girls for genital evaluation.

Sexually abused children need physical evaluation to determine if they have been injured, infected, or impregnated by the activity, and to reassure them about their bodies. The physical evaluation can be very frightening because it may involve sensations similar to those felt during the abuse. In order to cope, children need information about the purpose and process of the procedure, the sensations and emotions they can expect to experience, and training in how to manage their emotional responses. This protocol is offered as a structure for providing the information in a timely and effective way.

Adaptation, Psychological↗

Use of power spectral analysis of respiratory sinus arrhythmia to detect graft rejection.

Some evidence has suggested that graft rejection in heart transplant recipients is accompanied by sinus node dysfunction. To test this hypothesis the electrocardiograms of 21 orthotopic heart transplant recipients receiving cyclosporine were recorded at regularly scheduled biopsies. This resulted in 105 good quality recordings of at least 10 minutes each. All exhibited normal sinus rhythm. These recordings were then processed through patented digital routines that calculated the power spectrum of the RR intervals. All recordings exhibited Mayer wave and respiratory sinus arrhythmia (RSA) periodicities. Peak spectral power of RSA (PSP-RSA) demonstrated good repeatability at 2 weeks (r = 0.81). A paired t test comparing the baseline PSP-RSA in eight subjects who experienced rejection episodes with their individual average PSP-RSA during periods of rejection revealed a significant decrease (p = 0.039). As a global measure, PSP-RSA greater than 1 (natural logarithmic scales) demonstrated a sensitivity of 1.0, specificity of 0.42, positive predictive value of 0.22, and negative predictive value of 1.0. These tentative results demonstrate that PSP-RSA may be a sensitive, noninvasive marker for graft rejection of heart transplant patients receiving cyclosporine for immunosuppression. A larger, more extensive study needs to be conducted to confirm these results.

Adult↗

Procainamide-induced lupus erythematosus: report of a case with a large pericardial effusion and fluid analysis.

A patient with procainamide lupus erythematosus had a large pericardial effusion. As in other reported cases histology revealed a fibrinous mononuclear pericarditis and the pericardial fluid was a serosanguinous inflammatory exudate with a high LDH level and normal glucose concentration. The ANF and LE cell preparation were positive in the fluid but the C3 complement was normal. The frequency of pericarditis is similar in systemic and drug-induced lupus erythematosus yet low complement levels need not occur. Complement activation may therefore be unnecessary for the development of either type of lupus pericarditis.

Complement System Proteins↗