Mycobacterium simiae is commonly found in nature and its role as a pathogen has been controversial. A case of disseminated M. simiae infection with blood, pulmonary and cutaneous localization is reported here. The pathogenic role of M. simiae was clearly demonstrated as it was the only organism isolated from sputum, broncho-alveolar lavage fluid, as well as blood and skin tissue. Identification of M. simiae by conventional testing may be difficult. Analysis of fatty and mycolic acid patterns, as performed in this case, is necessary to confirm its identification.

AIDS-Related Opportunistic Infections↗

PubMedDate not supplied

Evaluation of a diode detector array for measurement of dynamic wedge dose distributions.

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Evaluation Studies as Topic↗

PubMedDate not supplied

Systemic prophylaxis with doxycycline in intestinal surgery on patients with high incidence of abnormal fecal flora.

Resistance of the fecal bacterial flora to doxycycline was studied before, during and after systemic prophylaxis with that agent in 24 patients undergoing surgery for complex intestinal disorders, 14 of whom had received antibiotics during the preceding 6 months. Fecal specimens for bacteriologic culture were obtained preoperatively, at operation and 3 days, 1 week and 4 weeks postoperatively. In nine patients (38%) there was dominance of doxycycline-resistant strains preoperatively. At 3 days and 1 week postoperatively the corresponding figures were around 55%. Dominance of doxycycline-resistant bacteria was found in altogether 20 patients at some time during the 4 postoperative weeks. At 4 weeks the fecal flora was normal in 22 of the 24 patients. Antibiotics other than doxycycline should be preferred for prophylaxis in patients undergoing complex, revisional or repeat bowel surgery, especially if they have received antibiotic treatment in the preceding 3-6 months.

Adolescent↗

PubMedDate not supplied

Morphometric and functional studies of proximal and distal colon in young and adult rats.

Net sodium and fluid absorption in the colon is higher in young than in adult rats. The mechanism behind the high absorption in young rats is not well understood. In this study, we investigated the structural and functional properties of the proximal and the distal colon in 20- and 40-day-old rats. The surface area of the mucosa along the luminal surface of the gut in relation to the mucosal volume (surface density) was determined by morphometry. Net sodium and water absorption was determined by in vivo perfusion experiments. The surface density of the mucosa was greater in the proximal than in the distal colon in both 20- and 40-day-old rats. No developmental change in the surface density of the mucosa occurred between 20 and 40 days of age, however, in either the proximal or distal colon. Net sodium and fluid absorption per unit of weight were higher in both segments in 20- than in 40-day-old rats, and higher in the distal than in the proximal colon in 40-day-old rats. We conclude that other factors than the absorptive area are responsible for the decrease in the net colonic sodium and fluid absorption observed during late postnatal development and for the differences in sodium net absorption between the proximal and distal colon in 40-day-old rats.

Aging↗

PubMedDate not supplied

Effect of E. coli ectotoxin on calcium and phosphate concentration in serum of dairy cows.

The injection of E. coli ectotoxin into eight healthy cows of the SRB breed induced a significant hypocalcemia and hypophosphatemia. A clinical profile similar to that normally seen in paresis puerperalis was also observed. These results confirm earlier observations that toxaemia can give rise to paralytic symptoms.

Animals↗

PubMedDate not supplied

Hypocalcaemia and Q-oTc interval in cows with parturient paresis.

The degree of hypocalcaemia was determined from serum total, and serum ionized calcium concentrations in 27 cows with parturient paresis. Electrocardiographic recordings were made just before the start of the intravenous calcium treatment. The T-oTc interval was determined, but could only be adequately measured in 16 cases because of inherent difficulties in recording from paretic animals. No significant correlation was found between the degree of hypocalcaemia and Q-oTc interval, whether the hypocalcemia was determined from serum total or serum ionized calcium concentrations. This study indicated that measurement of the Q-oTc interval was of very little value as a clinical test for detection of hypocalcaemia and indication of the degree of hypocalcaemia in parturient paresis.

Animals↗