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Biomedical subjects

L Larson

Publications and source records attributed to L Larson.

At least 19 recordsLinked to original sources
PubMed2000

Peek-a-boo fragile site at 16d associated with Tourette syndrome, bipolar disorder, autistic disorder, and mental retardation.

Five patients with a fragile site at 16q22-23 and neuropsychiatric disorders are reported. Three of five had Tourette disorder, three had mental retardation, two had bipolar disorder, and one had autistic disorder. During our attempts to study the fragile sites in more detail we were unable to reproduce the fragile sites found several years earlier. The potential relationship between the fragile sites and the neuropsychiatric disorders in these patients is discussed. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:69-73, 2000.

Adolescent↗
PubMed2000

Genomics.

Explore the source record for details and available documents.

Biotechnology↗
PubMed1999

An internal operation. How Granada Hills reinvented its management.

When the board of a California community hospital found that it had drastically miscalculated its earnings for 1998 and was actually in the red, trustees knew they had to act fast. Resisting the "cut and slash" advice of a turnaround specialist, the board chose to "reinvent" its management structure. That's how it could maintain its community health mission and still end up in the black.

California↗
PubMed1999

What every board should know.

Even the most experienced trustees can learn something new. Ther's no way you can do your job well without updating your knowledge of the field. Experts discuss what you need to know--and how you can go about learning it.

Adult↗
PubMed1999

The right thing to do: an ethical framework helps trustees lead the way.

Organizational ethics provides a process to consciously and consistently incorporate the hospital's values and the good of patients into all decisions. That responsibility falls squarely on the board. "Trustees are standing in two worlds," says Robert Potter. "One foot is in the hospital and one foot is in the community. No other group of people can fairly balance the interests of both."

American Hospital Association↗
PubMed1998

Alveolar-arterial oxygen gradient in acute pulmonary embolism in pregnancy.

OBJECTIVE: Our goal was to determine the prevalence of normal alveolar-arterial gradients in pregnant patients with documented pulmonary embolism. STUDY DESIGN: A retrospective chart review was performed on all pregnant women with pulmonary embolism at two large obstetric centers between 1990 and 1995. Alveolar-arterial gradients were calculated from room air arterial blood gas values and compared with values from patients who had been established as normal. RESULTS: Ten of 17 patients with pulmonary embolism identified had alveolar-arterial gradients that were normal. CONCLUSIONS: In our study 58% of pregnant women with documented pulmonary embolism had a normal alveolar-arterial gradient. This markedly differs from the published data in nonpregnant patients, in which the incidence of normal alveolar-arterial gradients in pulmonary embolism has ranged from 1.9% to 20%. This suggests that the alveolar-arterial gradient should not be used to determine the likelihood of pulmonary embolism in pregnant women because this could lead to the withholding of appropriate treatment for this life-threatening condition.

Adolescent↗