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Biomedical subjects

L L LaPointe

Publications and source records attributed to L L LaPointe.

At least 19 recordsLinked to original sources
PubMed2000

Multidimensional scaling of nasal voice quality.

Listeners judged the dissimilarity of pairs of synthesized nasal voices that varied on 3 dimensions. Separate nonmetric multidimensional scaling (MDS) solutions were calculated for each listener and the group. Similar 3-dimensional solutions were derived for the group and each of the listeners, with the group MDS solution accounting for 83% of the total variance in listeners' judgments. Dimension 1 ("Nasality") accounted for 54% of the variance, Dimension 2 ("Loudness") for 18% of the variance, and Dimension 3 ("Pitch") for 11% of the variance. The 3 dimensions were significantly and positively correlated with objective measures of nasalization, intensity, and fundamental frequency. The results of this experiment are discussed in relation to other MDS studies of voice perception, and there is a discussion of methodological issues for future research.

Humans↗
PubMed1999

Quality of life with aphasia.

This article considers quality of life (QOL) with aphasia. The problems surrounding definition and measurement of QOL are reviewed. Dimensions of QOL that have been suggested include elements relating to physical problems, the toxicity dimension, body image and mobility, communication, and psychological, interpersonal, spiritual, and financial issues. These issues are placed in the context of wider dimensions of satisfaction and life quality related to individuality, culture, and philosophical and time elements. Research on the illness experience is related to QOL. Research on QOL after stroke and aphasia is reviewed. Clinical approaches that integrate models of betterment of life quality in aphasia are suggested. Notions of coping and of Aristos, "making the best of a given situation," are considered in the discussion of adjustment and accommodation to life with aphasia.

Adaptation, Psychological↗
PubMed1998

Working memory and aphasia.

This study investigated the relationship between working memory capacity and reading comprehension in aphasia. A measurement of working memory capacity was obtained using a modified version of Daneman and Carpenter's (1980) Reading Span Task. Sets of sentences ranging in length from one to six words were presented to 22 aphasic subjects who were required to retain the terminal words following each sentence for subsequent recognition. The maximum number of words retrieved was used as an index of working memory capacity. Two versions of the task (listening and reading) were presented depending on the subjects' ability to read. Strong positive correlations were found between working memory capacity, reading comprehension, and language function. These results support the notion that the ability of aphasic individuals to comprehend language is predictable from their working memory capacities.

Adult↗
PubMed1996

Auditory vigilance in aphasic individuals: detecting nonlinguistic stimuli with full or divided attention.

Previous research (LaPointe & Erickson, 1991) has shown that aphasic individuals have difficulty, relative to control subjects, in monitoring for spoken words while performing a secondary task. This finding may indicate that aphasics have fundamental deficits in attention or that their linguistic deficits are simply exacerbated by dividing attention. Twenty subjects, 10 nonfluent aphasic and 10 nonaphasic adults, listened to two 10-min series of nonlinguistic acoustic stimuli across conditions of focused and divided attention. Subjects tried to identify target sounds interspersed with nontarget sounds. As in prior research, aphasic subjects performed less accurately on the auditory vigilance task during the divided attention condition, relative to the undivided attention condition and to control subjects. The findings suggest that deficient cognitive processing, intertwined with linguistic deficit, may underlie auditory comprehension deficits in aphasia and may help explain performance variation within aphasic individuals across tasks.

Aged↗
PubMed1989

Home treatment for aphasic patients by trained nonprofessionals.

Thirty-seven aphasic men received 8-10 hr of individual treatment each week for 12 weeks from a home therapist (wife, friend, relative) who was trained and directed by a speech pathologist. Treatment was followed by 12 weeks of no treatment. Patients were evaluated at entry and at 6, 12, 18, and 24 weeks after entry with a battery of speech and language measures. The group made substantial progress on all measures during the 12 weeks of treatment and ceased to progress when treatment was discontinued. Progress for the home treatment patients did not differ significantly from that of patients who received 12 weeks of individual treatment from speech pathologists or from that of patients for whom treatment was deferred for 12 weeks. Patient selection, training of the home therapists, and other methodological aspects are described to assist speech pathologists in making decisions about the use of trained volunteers in aphasia treatment.

Aged↗
PubMed1987

Lateral and anterior-posterior mandibular position discrimination by normal subjects.

This study examined and compared lateral and anterior-posterior (A-P) mandibular position discrimination for a group of twenty normal subjects (mean age = 26 years). A specially designed and constructed sliding scale required subjects to position their mandible precisely in the horizontal plane and to try to discriminate differences in the control of their mandibular position. The results revealed that subjects are more sensitive in detecting changes in the lateral positioning of their mandible than in the A-P positions. Subjects' difference limen (DL) values (threshold of discrimination between two positions) in detecting changes in mandibular position to the right of centre was 1.59 mm, and to left of centre was 1.41 mm. Subjects' DL values obtained with the mandible forward, and back of, the reference position were 1.39 and 2.61 mm respectively.

Adult↗
PubMed1986

Comparison of clinic, home, and deferred language treatment for aphasia. A Veterans Administration Cooperative Study.

Aphasic patients who met stringent selection criteria were assigned randomly to three groups: clinic treatment by a speech pathologist for 12 weeks, followed by 12 weeks of no treatment; home treatment by a trained volunteer for 12 weeks, followed by 12 weeks of no treatment; or deferred treatment for 12 weeks, followed by 12 weeks of treatment by a speech pathologist. At 12 weeks after entry, language measures indicated that the clinic-treatment patients made significantly more improvement than did the deferred-treatment patients, and improvement in home-treatment patients did not differ significantly from either clinic- or deferred-treatment patients. At 24 weeks after entry, after deferred-treatment patients had received clinic treatment, there were no significant differences among the groups. These results suggest that clinic treatment for aphasia is efficacious, and delaying treatment for 12 weeks does not compromise ultimate improvement.

Aged↗
PubMed1985

Bite force discrimination by individuals with complete dentures.

The purpose of this study was to determine whether differences existed in interincisor bite force discrimination between a group of subjects wearing complete dentures and a group of dentate individuals. It was hypothesized that biting force is monitored at least in part by the sensory mechanism within the PDL and that the absence of the PDL would result in reduced bite force discrimination. A specially designed strain gauge scale was constructed for the measurement of bite force. Bite force discrimination was assessed at three different standards including 500, 1000, and 3000 gm. Data analysis revealed that, overall, bite force discrimination was not significantly different for the two groups. However, at the lightest standard of 500 gm, the dentate group performed significantly better (p less than .05) than the denture wearers. It is concluded that the sensory system within the PDL plays a role in monitoring bite force discrimination.

Adult↗
PubMed1977

Base-10 programmed stimulation: task specification, scoring, and plotting performance in aphasia therapy.

This report explains and advocates the applicability of time-series designs to document the effects of therapy with aphasic subjects; it describes a measurement system that contributes to organization of therapy, task specification and scoring, and graphic display of change in speech and language behaviors. Examples of patient performances illustrate the application of Base-10 Programmed Stimulation to therapy with aphasic persons.

Aphasia↗