Search PubMedSearch

Biomedical subjects

L L Barr

Publications and source records attributed to L L Barr.

At least 19 recordsLinked to original sources

Induction of gastroduodenal prolapse by antral heterotopic pancreas.

Ectopic pancreas is the most common congenital anomaly in the gastric antrum. In some patients, there is a distinct tendency for this lesion to produce intermittent crampy abdominal pain by provoking gastroduodenal prolapse. This condition should be considered after a more distal prolapse from intussusception is excluded. An upper gastrointestinal series performed during an episode of symptoms may be diagnostic of this entity.

Choristoma

Quantification of intravenous contrast-enhanced Doppler power spectrum in the rabbit carotid artery.

In vivo evaluation of Doppler contrast agent (DCA) enhancement has been principally qualitative. To quantitate the enhancement of the Doppler signal by perflubron emulsion, an investigational DCA, the audio-Doppler signal from the rabbit carotid artery was recorded during 0.5-ml/kg incremental doses to a total dose of 2.5 ml/kg. A representation of the recorded signal intensity, the Doppler power spectrum (DPS), was determined using a personal computer and commercially available software package. The dose related enhancement from perflubron emulsion was linear (r = 0.986, p = 0.0124) with a 710% (8.5 dB) overall enhancement at 2.5 ml/kg (p = 0.0001). Significant differences in enhancement could be detected with doses as low as 1.0 ml/kg and compared favorably with observer assessment of dose-related enhancement. This relatively simple method of computer analysis can quantify in vivo Doppler signal intensity and enhancement by perflubron emulsion and may enable quantitative comparisons between different DCAs.

Animals

Elbow.

Explore the source record for details and available documents.

Adolescent

Sonography in the infant with acute abdominal symptoms.

The sonogram is a reliable diagnostic tool in the evaluation of acute abdominal disorders in infants and children. Portability, noninvasiveness, and ease of examination make sonography an invaluable diagnostic method. This article considers the principle acute disorders of infancy and childhood that are minimal to sonographic diagnosis. Included are pyloric stenosis, appendicitis, necrotizing enterocolitis, intussusception, as well as unexplained abdominal distention and acutely presenting masses. Although some of these entities have nonspecific sonographic appearances, consideration of age, symptoms, and laboratory results usually permits a specific diagnosis.

Abdomen

Understanding the process of quantitative ultrasonic tissue characterization.

Because the human vision system cannot distinguish the broad range of gray values that a computer visual system can, computerized image analysis may be used to obtain quantitative information from ultrasonographic (US) real-time B-mode scans. Most quantitative US involves programming an off-line computer to accept, analyze, and display US image data in a way that enhances the detection of changes in small-scale structures and blood flow that occur with disease. Common image textural features used in quantitative US tissue characterization consist of first-order gray-level statistics (eg, occurrence frequency of gray levels independent of location or spatial relationship) and second-order gray-level statistics dependent on location and spatial relationship, including statistical analysis of gradient distribution, co-occurrence matrix, covariance matrix, run-length histogram, and fractal features. A customized tissue signature software has been developed to analyze image data obtained from clinical US scanners. Means comparison testing and multivariate analysis techniques are used to compare the numbers generated for a particular region of interest. By integrating these techniques into the radiologist's interpretation of the sonogram, the quantitative information gained may lead to earlier detection of lesions difficult to see with the human eye.

Humans

Age-related variability in elbow joint capsule thickness in asymptomatic children and adults.

The purpose of this study was to establish normal ultrasonographic measurements for elbow joint capsule thickness in children. Transverse posterior ultrasonographic images of 53 elbow joints in asymptomatic patients were digitized, and off-line measurements were performed and compared to the corresponding scale present on each image to yield a reliable measurement in millimeters. Joint capsule thickness measurements regressed with age. Significant differences existed between three age groups. Joint capsule thickness is under 1 mm in children 1 month to 2 years of age, increased significantly to just over 1 mm from 2 to 15 years of age, and approached 2 mm in thickness at and after 15 years of age.

Adolescent

Ultrasonography of acute epitrochlear lymphadenitis.

While the clinical symptomatology and radiographic findings of acute suppurative infection of the epitrochlear lymph nodes of the arm have been previously described, ultrasonographic findings have not been reported. This case report demonstrates that sonographic identification of enlarged epitrochlear lymph nodes immediately confirms the diagnosis. We summarize the clinical, radiological, and sonographic findings of acute suppurative infection of the epitrochlear lymph nodes.

Acute Disease

Intraoperative uses of ultrasound in the pediatric neurosurgical patient.

Ultrasound imaging has become a common method for intraoperative evaluation of the central nervous system. Real-time monitoring aids in guidance for aspiration of fluid collections and placement of catheters as well as the localization and evaluation of masses, and confirmation of their complete removal. Color Doppler is useful in the evaluation of blood flow in arteriovenous malformations, aneurysms, and neoplasms. Consultation among the ultrasound staff, neuroradiologists, and neurosurgeons before the operative procedure maximizes the usefulness of ultrasound, thus aiding in the success of surgery.

Blood Flow Velocity

Conservative management of large ovarian cysts in children: the value of serial pelvic ultrasonography.

BACKGROUND: The management of large ovarian cysts in children is controversial and complicated by a poorly understood natural history. The purpose of this study was to determine the course of sonographically detected large ovarian cysts in a pediatric population. METHODS: All pelvic ultrasonograms in which an ovarian cyst was detected during a 6-year period were reviewed. Large cysts were defined as those of more than 5 cm in any dimension or a volume of more than 13 cc. Clinical data and follow-up was derived from either the hospital chart or by telephone interview. RESULTS: Large ovarian cysts were detected in 92 of 191 patients (48.2%). The average age was 14.9 years (range, 3 to 22 years). Eight patients were premenarchal. In 23 patients, surgery was performed, with findings of neoplasm in 10. In patients managed without surgery and with follow-up, 46 of 51 cysts (90%) decreased in size or completely resolved. Both complex and simple cysts resolved. CONCLUSIONS: Most large ovarian cysts in children (simple or complex) may be safely followed with serial pelvic ultrasonography, because most cysts will either decrease in size or resolve. Neither the character of the cyst nor the size reliably predicted clinical outcome. The decision for surgical intervention should not be based solely on ultrasonographic characteristics, but other factors such as severe symptoms, complications associated with the large mass, other evidence suggestive of neoplasm, ovarian source in doubt, or whether the cyst fails to resolve or decrease in size on follow-up ultrasonography.

Adolescent

Color Doppler US imaging during pediatric neurosurgical and neuroradiologic procedures.

Experience with color Doppler imaging (CDI) during 16 pediatric intraoperative and one percutaneous neuro-radiologic procedures was reviewed to assess whether CDI increased the success rate or decreased the procedure time, thus contributing substantially to procedure performance. Intraoperative CDI was used to rapidly identify abnormal vessels or displacement of normal vessels and correlated with preoperative studies. In six cases (four vascular malformations, one mycotic aneurysm, and one hamartoma), surgical resection was altered on the basis of flow information obtained. In one case of percutaneous embolization of a Galenic malformation, CDI provided information contributing to the cessation of the procedure. In six cases (debulking of three gliomas, resection of one vascular malformation, and two biopsies of nonneoplastic conditions), information was added but did not alter the surgical approach. In the remaining four cases (three cerebrospinal fluid drainage procedures, one posterior fossa decompression), no additional information was obtained. Consultation among the ultrasound staff, neuroradiologists, and neurosurgeons before the operative procedure maximized the usefulness of CDI, thus aiding in the success of surgery.

Adolescent

Sonography of the normal elbow.

Sonography was performed in 30 normal patients, neonatal to 45 years old, to illustrate our technique for complete and rapid examination of the elbow joint. Sonography is an easy, noninvasive method of evaluating the articulating surfaces, tendinous insertions, and supporting soft tissues of the elbow joint. Reliable identification of both normal and diseased anatomy is possible at all ages. Familiarization with the sonographic appearance of the six elbow ossification centers aids in sonographic interpretation.

Adolescent

Enteric duplication cysts in children: are their ultrasonographic wall characteristics diagnostic?

We reviewed eight cases of gastrointestinal duplication cysts to determine whether the combination of an echogenic inner mucosal layer and hypoechoic outer muscular layer could be seen consistently enough to be of diagnostic value. We compared our findings to those seen in twenty-seven other abdominal cysts and conclude that when identified together, the two layers are highly suggestive, if not completely diagnostic of enteric duplication cysts.

Abdomen

Significance of age, duration, obstruction and the dissection sign in intussusception.

A retrospective study of sixty consecutive cases of proven intussusception with attempt at contrast enema reduction was performed to evaluate currently proposed contraindications to such reduction. When patient age, duration of symptoms, presence of small bowel obstruction and presence of a dissection sign were considered alone, none of the findings indicated irreducibility. Our overall reduction rate was 72% with a complication rate of 3%. This is similar to previously reported series and we concur with more recent publications that the only contraindications to non-surgical reduction of intussusception are free intraperitoneal air, peritonitis or evidence of infarcted bowel. Only when we encountered a combination of symptoms being present for greater than 48 hours and the presence of both small bowel obstruction and a dissection sign was reduction likely to be unsuccessful. However, the presence of a prognostic indicator occurring alone should not be considered a contraindication.

Age Factors