[Surgical problems after radiation therapy (author's transl)].
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Biomedical subjects
Publications and source records attributed to L Koslowski.
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The indication for ileorectal anastomosis after colectomy is most likely given - with all reservations - in cases of ulcerative colitis and polyposis coli, not so often in Crohn's disease. Our own studies of dwarf pigs have shown that no qualitative changes take place in the histochemical characteristics either of ileum mucosa or in that of the rectum, following ileorectostomy. Late results of shelling out the rectal mucosa, and the tendencies towards constructing a reservoir of terminal ileum in the pelvis, remain to be seen. While keeping the risks at a justifiable level it should be our aim to enable our often still young patients to lead a normal life without social handicaps.
Since 1972 we have been using a new method of gastric replacement which was developed at our hospital. The reconstruction of passage is achieved by iso-anisoperistaltic interposition of two jejunal segments (30:10 cm). The reversed segment causes delayed and intermittent emptying of the above located isoperistaltic segment. Until now this type of gastric replacement has been performed in 62 patients. Postoperative mortality was 11.3%; so far the longest survival time is nearly 8 years. By the reservoir function of the jejunal interposition digestion and absorption are essentially improved, resulting in a better quality of life for the patient. This type of gastric replacement is now used as a routine in all curative gastrectomies, provided there are no contraindications on account of the patient's age or general condition.
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Following experiments in animals, a new procedure for gastric replacement after total gastrectomy has been employed since 1972. Digestive tract continuity is reestablished by interposing two jejunal segments, on iso- and the other aniso-peristaltic, between the esophagus and the duodenum. The proximal isoperistaltic segment should be between 30 and 40 cm in length, while the distal anisoperistaltic segment should measure 10 cm. The latter segment replaces the pylorus and produces delayed intermittent emptying of the proximal iso-peristaltic segment. Their progressive dilatation results in the development of a new reservoir which reaches its maximum volume after 6 to 12 months. Radiological, cinematographic, and endoscopic examination in 58 patients in whom this reconstruction had been performed demonstrated that function was excellent. Results of metabolic studies and tests for clinical function confirmed the value of the method, which has definite advantages over previous techniques employed to reestablish continuity. For this reason, the method has become a routine procedure in patients requiring extensive total gastrectomies.
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A transhepatic drainage tube was used in 27 patients suffering from echinococcus alveolaris of the liver of malignant process of the portal fissure from 1967 to 1978. If an hepatocholangioenterostomy is not possible, another surgical palliative procedure is necessary for drainage of the bile. The transhepatic drainage tube is a simple palliative method. The technique of this procedure, the indications, the possible complications, and the advantages are reported.
From 1959-1976, 183 gastrectomies were performed in the Chirurgische Klinik of the University of Tübingen, for gastric carcinoma. The average mortality for the operations was 19.1%, postoperative complications occurred in 41% of the cases. The most frequent cause of death was failure of the oesophageal anastomoses. The two methods most commonly used, Longmire-Gütgemann's interposition of small intestine and oesophagojejunostomy with Braun's anastomosis, differ considerably in the complication rate and mortality. The interposition of small intestine, with almost indentical preoperative and intraoperative risk factors, an operative mortality of 4.4% and distinctly less danger of anastomotic failure was shown to be superior to the technically simple oesophagojejunostomy. The formation of an "artificial stomach" in gastrectomy is therefore to be preferred to all other surgical methods of reconstruction of the intestinal passage, not only because of the better late results but also because of the better early results.
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After a thermal trauma similar changes of Mg and Zn levels in serum are observable. During the initial period of shock the concentration of both elements increases as a consequence of damage of cellular and subcellular compartments. During the catabolic phase a deficiency syndrome occurs as a result of renal excretion, loss through the wound secretion, and demarcation of necrotic tissue. On the other hand increasing requirements of Mg and Zn appear because of the anabolic process of wound healing. From these reasons a substitution of both elements is recommendable in all cases of proved deficiency after burns.
One-third of all surgical patients develop a deep phlebothrombosis. This frequency of thrombosis after injuries of the lower extremities is estimated at 65%. Most of the thromboses do not become clinically manifest. Ninety-two percent of all fatal pulmonary embolisms originate from a clinically inapparent thrombosis. The ideal prophylaxis should compensate for the undesired effects of an operation or injury on the coagulation system, without subjecting the patient to the danger of elevated tendency to bleed. The discussion of this subject should help to clarify the present successes and risks of thromboembolism prophylaxis and therapy.
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