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Biomedical subjects

L Knight

Publications and source records attributed to L Knight.

At least 37 records · Page 2Linked to original sources
PubMed1977

Three year experience with percutaneous introduction of inferior vena cava filter.

Fifteen patients with recurrent pulmonary embolism were treated with a Mobin-Uddin umbrella filter (UF) introduced percutaneously via femoral vein. There were not technical difficulties, bleeding, or migration of the UF. The incidence of lower extremity edema or phlebitis was not higher than in patients with transjugular application of the UF or in patients with surgical inferior vena cava clipping. Two patients had fatal recurrent pulmonary embolism: in one of them the UF was positioned correctly in the vicinityof the renal veins; in the second the UF was placed too low and a large clot may have formed proximal to the UF. The transfemoral approach of the UF insetion represents a significant simplication of the inferior vena caval interruption, but it can only be used if thrombi are excluded by venography in the iliac vein and inferior vena cava. The UF should be placed as close as possible to the orifices of the renal veins to prevent a thrombus formation proximal to the filter.

Adolescent↗
PubMed1976

Peripheral angiograph enhancement by long leg pneumatic boots.

In patients with arterial occlusive disease it is virtually impossible to predict the speed of blood flow due to the presence of stenoses, occlusions, and collaterals. Repeated exposures and injections can be avoided by the use of pneumatic boots which increase peripheral blood flow by reactive hyperemia, are well tolerated by patients, and decreases the pain associated with injection of contrast material.

Angiography↗
PubMed1976

The effect of valium on myocardial blood flow.

The effect of Valium on coronary blood flow was studied. In 18 patients undergoing coronary angiography, total and regional myocardial blood flow was determined by the 133Xe wash-out technique. A total of 39 pre- and 39 post-Valium injection wash-out curves were constructed. Results indicate (99% confidence) that intravenous Valium injection (0.1 mg/kg body weight) decreases myocardial blood flow 12--15%.

Angiography↗
PubMed1976

Alveolar rhabdomyosarcoma involving the heart. An echocardiographic, angiographic and pathologic study.

A 12-year-old girl, who had had an above-knee amputation of the left leg for a soft tissue sarcoma six years prior to this admission, presented with syncope, angina, and signs of aortic stenosis. Echocardiography demonstrated a mass arising from the interventricular septum with obstruction of the left ventricular outflow tract and aortic valve. Cardiac catheterization and angiography confirmed these findings. At operation, a tumor was found involving the interventricular septum. Histologically, it was an alveolar rhabdomyosarcoma, and it appeared similar to the previous tumor. The patient was treated by partial surgical resection, cytotoxic drugs and localized radiation therapy and has been followed by serial echocardiography.

Cardiac Catheterization↗
PubMed1976

Hemodynamic assessment of obstructive aortoiliac disease.

Angiographic demonstration of obstructive aortoiliac disease is of paramount importance prior to surgery. Obstructive disease in the femoral popliteal system can only be surgically relieved if inflow is adequate. Severely stenotic lesions may be missed by angiography due to the oblique course of the iliac arteries and inability to obtain right angle views. Translumbar downstream catheterization of the abdominal aorta and puncture of both femoral arteries allows simultaneous pressure recordings. The injection of 30 mg of papaverine into the femoral artery assures maximal vasodilatation mimicking conditions under exercise. A minimal gradient at rest may become obvious following the injection of papaverine, indicating hemodynamically significant disease and warranting surgical correction. The technique has proved to be simple and valuable, and there have been no complications.

Aorta, Abdominal↗
PubMed1975

Methadone-induced pulmonary edema.

A patient with methadone-induced pulmonary edema had increased extravascular water in the lungs and a reduced total vascular albumin space. Diuresis resulted in hypotension. These observations suggest that the appropriate treatment of this condition should be ventilatory support and restoration of plasma oncotic pressure with albumin. Diuretic therapy should be used with caution.

Adult↗
PubMed1975

Massive pulmonary gangrene: a severe complication of Klebsiella pneumonia.

SUMMARY: Massive pulmonary gangrene developed in two patients. Review of the literature reveals 10 other case reports of pulmonary gangrene complicating lobar pneumonia. Among the total of 12 patients whose cases have now been reported, all 4 patients who were treated nonsurgically died and the 8 who underwent surgical resection of the gangrenous lung survived. The present report emphasizes the necessity of early recognition and appropriate surgical treatment for a successful outcome.

Adult↗
PubMed1975

Coarctation of the aorta associated with aortic valvular atresia.

The aortas in 41 specimeans of aortic atresia (ten with associated mitral atresia) were studied for the presence of coarctation of the aorta. The basic lesion, causing varying degrees of obstruction, was observed in 31 instances (75%), 24 minor, seven with major degrees of obstruction. In half, the aortic lesion lay proximal to the ductus, and in the majority of the remainder, opposite the ductus arteriosus. The location of lesion and degree of obstruction was essentially the same whether aortic atresia occurred alone or in association with mitral atresia. Angiography is a fairly reliable method of identifying coarctation associated with aortic atresia. An additional point of interest was that in aortic atresia alone there was strong dominance of the male sex, while this tendency was not observed when mitral atresia was associated with aortic atresia.

Aorta↗