Two cases of apparent silicone allergy.
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Biomedical subjects
Publications and source records attributed to L Kirwan.
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Nine patients with open wounds are reviewed. All wounds were debrided prior to application of Biobrane. Silver sulfadiazine was applied twice daily. All healed uneventfully after closure. Biobrane is recommended for treatment of difficult and large open wounds; its use reduces evaporative loss and bacterial proliferation, enabling development of a healthy wound base suitable for grafting or delayed closure. This approach can prevent the necessity for flap repair and reduce pain during wound dressing. Wounds such as lower extremity ulcers are often resistant to therapy. Repeated debridements may result in further desiccation without progression of wound healing. Biobrane-treated wounds develop a healthy granulating base which can be grafted or closed.
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A report of a case of primary hyperparathyroidism presenting as spinal cord compression due to a brown tumour of the vertebra is presented. Coexisting chrondrocalcinosis illustrates one of the several radiological features seen in hyperparathyroidism.
Traditionally, frailty has been conceptualized as reflecting an inevitable decline in abilities usually associated with physical aspects of aging. More recent thinking now sees frailty as reflecting an interaction among individual factors and a range of environmental elements. These emerging models, however, continue to consider frailty as a condition that resides within the individual rather than a situation that exists for the individual. We present a new model that defines frailty as occurring when there is diminished ability to carry out the important practical and social activities of daily living. Factors related to the occurrence of frailty are considered, as are the theoretical and practice implications of viewing frailty as a social construction.