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Biomedical subjects

L Kennedy

Publications and source records attributed to L Kennedy.

At least 127 records · Page 7Linked to original sources
PubMed1982

SSI: trends and changes, 1974-80.

By the end of 1980, the Supplemental Security Income (SSI) program was making monthly cash assistance payments, averaging $170, to almost 4.2 million aged, blind, and disabled persons. When SSI payments began in January 1974, the number of recipients was 3.2 million and the average payment was $117. Since 1975, both SSI payments and Social Security benefits have been automatically adjusted each year to correspond with increases in the Consumer Price Index. A number of other trends in addition to growth can be discerned in the size of the population served, as well as in their categorical, geographic, and age distributions. This article discusses some of these trends and changes, using program data for the end of each calendar year through 1980. It also presents a brief summary of the program at the end of that period.

Adolescent↗
PubMed1981

Non-enzymatically glycosylated serum protein in diabetes mellitus: an index of short-term glycaemia.

We measured non-enzymatically-glycosylated serum protein by a colorimetric assay in 107 diabetic and 82 control subjects. The mean level in diabetics was more than twice that in controls. Cross sectional and longitudinal studies in diabetic patients showed that glycosylated serum protein levels correlated with both fasting serum glucose and glycosylated haemoglobin levels. The correlation between glycosylated serum protein and fasting serum glucose was closer in Type 2 than in Type 1 diabetes. Treatment aimed at improving control in eight poorly controlled diabetic patients resulted in a 37% mean fall in glycosylated serum protein within one week, whereas glycosylated haemoglobin decreased only 8%. These studies confirm that non-enzymatic glycosylation of serum proteins is enhanced in diabetes. Measurement of glycosylated serum protein appears to provide an index of glycaemia over the preceding several days. It has the advantage of detecting improvements in glycaemic control much sooner than does glycosylated haemoglobin measurement.

Adult↗
PubMed1980

HLA antigens and affective disorder: a family case report.

A family of 6 affective ill siblings is described. Two suffered from bipolar illnesses, 2 from recurrent unipolar illness, and the remainder showed alcoholism, depression and schizo-affective disorder. HLA typing revealed that all the tested members shared the antigens A3 and B7. Because only ill members were available for testing, there was insufficient information in the family to draw any definite conclusion as to whether these antigens were linked to the illness. However, the observation is of some interest in the light of other recent reports which have suggested that these 2 antigens are associated with affective disorder.

Adult↗
PubMed1980

SSI payments to lawfully resident aliens, 1978-79.

Under the supplemental security income program, persons who are not citizens of the United States but are otherwise eligible may, under current law, receive SSI payments if they have been lawfully admitted to the country for permanent residence or are permanently residing here under color of law. The report examines data on noncitizens among a group of recent SSI awardees, including their country of birth, length of residence in the United States, and certain demographic characteristics. The group is also compared with citizens awarded payments in the same period in terms of age, sex, income, and amount of SSI payment. In the 8 months from September 1978 to May 1979 about 6 percent of the 273,000 awards went to noncitizens. Almost half of them had lived in the United States at least 5 years at the time of the first award. As a group they are older than the citizens and have less income, as their higher SSI payments indicate.

Adolescent↗
PubMed1979

An immunogenetic basis for the tissue involvement in Behçet's syndrome.

The multifocal involvement in Behçet's syndrome was grouped into a spectrum of four types, three of which appeared to have an immunogenetic basis. HLA-B5 was related to the ocular type of Behçet's syndrome (relative risk 7.3), HLA-B27 to the arthritic type (relative risk 12.1) and HLA-B12 to the muco-cutaneous type (relative risk 3.9). The concept that recurrent oral ulceration and Behçet's syndrome may belong to a disease spectrum is substantiated by the natural course of the disease. Furthermore, patients with recurrent oral ulcers share with the muco-cutaneous type of Behçet's syndrome a significantly increased frequency of HLA-B12 (relative risk 2.6). The HLA markers may also prove to be significant in the differential diagnosis and prognosis of a disease which may present under a confusing variety of clinical manifestations.

Adolescent↗
PubMed1979

Renal reflux, scarring, cystometrography and tissue types.

Four families with a variety of renal tract abnormalities including reflux, cortical scars, atrophy and duplex systems are described. Cystometrograms in eight with reflux and scars did not show any evidence of outflow high pressure systems. Tissue typing was carried out in a proportion of affected and unaffected family members, and with the addition of another reported family that had been tissue typed, showed an increase in A9, B8 and homozygosity in the families with these abnormalities. A retrospective survey of transplanted patients with tissue type A9 showed a higher prevalence of pyelonephritis and associated abnormalities than other diseases leading to end stage renal failure.

Cicatrix↗
PubMed1975

Ankylosing rheumatoid arthritis.

The study concerns the clinical, haematological, serological, radiological and histocompatibility antigenic status of eleven in-patients suffering from long-standing sero-positive rheumatoid arthritis at the Royal Hospital and Home for Incurables in London. The study revealed a striking degree of widespread bony ankylosis affecting the peripheral joints and cervical spine. In large part, this bony ankylosis accounted for the disability but it is considered that the cervical spine ankylosis may protect the spinal cord from damage. The absence of the histocompatability antigen HLA 27 is a useful pointer in the exclusion of Ankylosing Spondylitis. Despite the clinical impression that the disease was inactive, the elevated sedimentation rate (23-66, mean 41 mm) suggests that the rheumatoid process remains active.

Aged↗