A male laboratory assistant working in a metallurgical laboratory with airborne exposure to nickel dust developed highly pruritic, rosacea-like symptoms. The symptoms cleared within eight days without treatment when the patient was off work. Patch testing confirmed nickel allergy. Based on the patient's work and clinical history it was evident that occupational exposure to airborne nickel induced the highly abnormal rosacea-like symptoms, not previously reported from nickel.

Adult↗

PubMedDate not supplied

Allergic onycholysis and paronychia caused by cyanoacrylate nail glue, but not by photobonded methacrylate nails.

Artificial acrylic nails may induce side effects such as fingertip dermatitis, periungual dermatitis, onycholysis, paresthesiae, Raynaud's phenomenon, ectopic facial involvement, and allergic contact dermatitis. We present a patient who developed allergic onycholysis from a cyanoacrylate used in a nail adhesive. She was able to use photobonded sculptured nails because they contain methacrylates that do not cross-react with cyanoacrylates.

Adult↗

PubMedDate not supplied

Occupational allergic contact dermatitis from alkylammonium amidobenzoate.

Quaternary ammonium compounds are water-soluble antimicrobials which are widely used in disinfectants, sterilizers, skin cleansers and antiseptic creams. One quaternary ammonium compound, alkylammonium amidobenzoate (Osmaron B) has for decades been used in udder ointments. Here we present a ship technician with occupationally induced sensitization to alkylammonium amidobenzoate. The diagnosis was reached only when it emerged, after careful questioning, that the patient was exposed to a substance peculiar to his workplace but not to his occupation and was then patch tested for it. It turned out that an udder ointment had been used at the patient's workplace as a hand ointment. Patch testing was positive to the patient's hand ointment, and Osmaron B at 0.1-0.01% in petrolatum. Other sensitizing quaternary ammonium compounds, namely benzalkonium chloride, benzethonium chloride, benzoxonium chloride, N-benzyl-N,N-dihydroxyethyl-N-cocosalkyl-ammonium chloride, cetalkonium chloride, cetylpyridinium chloride, cetrimonium bromide, chloroallylhexaminium chloride, dequalinium chloride, domiphen bromide, methylbenzethonium chloride and 2,3-epoxypropyl trimethyl ammonium chloride are reviewed briefly. The importance of patch testing to all materials in use by the patient is emphasized. It is also important to select non-allergenic hand creams for use at work places.

Benzoates↗

PubMedDate not supplied

Occupational skin diseases.

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Allergens↗

PubMedDate not supplied

Lymphocytes and Langerhans cells in allergic patch tests.

An immuno-histochemical study of immuno-competent cells in the skin during fully developed 3-7 d patch tests was performed. Most inflammatory cells were OKT 11 positive T-lymphocytes. The majority of these cells were of the helper/inducer phenotype (OKT 4+), but in the later stages a relative increase of OKT 8+ cells was seen in 5 specimens out of 20. A focal decrease of OKT 6+ Langerhans cells was observed in the epidermis, while their number increased considerably in the dermis. Also observed was an inflammatory reaction of hair follicles with moderate numbers of OKT 6+ cells in the peribulbar infiltrate. This indicates that hair follicles may possibly act as shunt pathways for allergens.

Allergens↗

PubMedDate not supplied

Epoxy dermatitis.

Dermatitis caused by exposure to epoxy resin compounds was observed in the 1950s, shortly after epoxy resins were introduced. Following a description of the chemistry and the use of epoxy compounds, the authors discuss delayed and immediate allergic epoxy dermatitis and irritant epoxy dermatitis as well as factors such as exposure and skin testing.

Dermatitis, Occupational↗

PubMedDate not supplied

Knuckle pads from boxing.

A 21-year-old man developed painful hyperkeratotic, fissured, callosities on his knuckles ("knuckle pads") after having boxed for five evenings a week for six months. Boxer's knuckle pads are one type of traumatic skin injury regularly found in athletes, such as "jogger's toe", "athelete's nodule", "jog-ger's nipple", "runner's rump", "runner's bump", "rower's rump", "tennis toe", "skier 's shin", "surfer's nodule" "black heel", "black palm", "jazz ballet bottom" and "stria distensae". These types of traumatic skin injuries are briefly reviewed here.

Adult↗

PubMedDate not supplied

Allergic contact dermatitis from 2-hydroxyethyl methacrylate in an adhesive on an electrosurgical earthing plate.

A highly (meth)acrylate-allergic patient underwent surgery because of nodular struma. Three days after her operation she developed an itching dermatitis on her left thigh. She came to our attention 18 days after the operation, because of an oozing, highly pruritic dermatitis, 8 x 19 cm in width on her left thigh, at the site where an electrosurgical earthing plate had been used during the surgery. It was revealed that the pressure-sensitive adhesive of the pad contained 2-hydroxyethyl methacrylate (2-HEMA) to which the patient earlier had had an allergic patch test reaction. The patient was negative on patch testing to other (meth)acrylates present in the pad. Patients should be questioned about possible methacrylate sensitivity before methacrylate-containing electrosurgical earthing plates are used during surgery. Allergic contact dermatitis caused by acrylic adhesives is briefly reviewed.

Adhesives↗

PubMedDate not supplied

Guess What! Occupational contact psoriasis.

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Dentistry↗