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Biomedical subjects

L K Lee

Publications and source records attributed to L K Lee.

41 records · Page 3Linked to original sources

Selective area tuberculosis surveys in Singapore 1978.

A random population sample survey in Singapore 1975 revealed that a relatively high proportion of active pulmonary tuberculosis patients remained undiagnosed, mainly in the older age groups. Previous studies disclosed the cause to the lack of symptoms of concern in these patients. A new programme was devised to discover hidden elderly patients by mass chest X-ray screening of population aged 45 years and older living in areas with known high incidence of tuberculosis. The yield of cases was less than expected mainly due to the dislocation and dispersion of population from recent extensive urban re-development in Singapore. Nevertheless the results were comparable to the most productive case finding programme carried out in this department.

Aged↗

Bacteriological measures for the detection of cases of pulmonary tuberculosis.

There is a need for more detailed information on the relative merits of the culture and direct sputum smear examination methods, separately and in various combinations, using one or more sputum specimens. The efficiency and relative cost of different bacteriological measures for the detection of cases of pulmonary tuberculosis, in the conditions of the Singapore tuberculosis control programme, are demonstrated. The findings provide guidance for deciding how, and in what order, these bacteriological measures should be used, and may assist planners and executives of national tuberculosis control programmes in the rational commissioning of laboratory facilities that already exist or are to be established.

Bacteriological Techniques↗

Differential scanning calorimetric measurements on human lenses.

Differential scanning calorimetric measurements were performed between - 30 degrees C and 15 degrees C. The cortical sections of normal human lenses usually show one endotherm at the melting point, while the nucleus indicates a composite endotherm that can be separated into two endotherms with two melting points. Cataractous human lenses usually have composite endotherms from the cortical, intermediate as well as nuclear regions. We interpret the different endotherms as representing different kinds of freezable water contents: free water and partially bound water. Both in normal and cataractous human lenses, there is an appreciable amount of non-freezable water. The amount of non-freezable water is less in cataractous lenses than in normal lenses, indicating a syneretic process as a cause of cataract formation.

Body Water↗