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Biomedical subjects

L Jirásek

Publications and source records attributed to L Jirásek.

At least 19 recordsLinked to original sources
PubMed2001

[Therapy of pruritus using ultraviolet irradiation in patients on hemodialysis].

BACKGROUND: Patients with chronic renal insufficiency (CHRI) frequently suffer from generalized pruritus, which is difficult to palliate. One of the treatments with favourable effect on pruritus is UV radiation. METHODS AND RESULTS: Fifteen patients were exposed to UVB radiation in doses from 20 to 45 s or from 1 min and 20 s to 18 min (i.e. 0.09-0.18 J/cm2 to 1.9-4.32 J/cm2). Ten of the treated patients reported a marked regression of pruritus, three a slight relief and two of them did not notice any change in the intensity of itching. Another four patients were exposed to the UVA radiation from 0.5 J/cm2 to 10.0 J/cm2 With exception of one female patient non-of them revealed any improvement in the intensity of pruritus the irradiation. CONCLUSIONS: UVB is probably highly effective on inhibition of pruritus and thus can be used as an efficient method, which extends contemporary antipruriginous treatment of patients with CHRI. However, so far it is difficult to explain its favorable effect.

Adult↗
PubMed1987

Epidemiology of nickel allergy.

In 2400 consecutive patients at 8 clinics in 5 countries, nickel hypersensitivity was found in 176 cases (7.3%), 19 male (2.1%) and 157 female (10.5%). The incidence ranged from 15 to 38 cases in 300 patients of every department (5.0% Sofia to 12.7% Erfurt). 60.6% of the nickel positives were schoolgirls or younger than 25 years. The exposure time was 3 years, in 49% 1 year or shorter. Most cases (75%) are not occupationally acquired, but due to costume jewelry (31.8%), wrist watches (23.3%), metal clothing buckles (3.4%) including jeans buttons. Job dependent nickel dermatitis is often (36/51 cases) linked with wet work. Atopic dermatitis was found in 8.3% of female nickel allergy. Nickel positivity without a dermatitis history was seen in 9/176 cases (5%). Nickel allergy will become a sex-indifferent phenomenon in Europe, because of the changing customs of adornment.

Dermatitis, Contact↗
PubMed1981

Sacroiliac joints in chronic dermatoses.

In 34 patients with different chronic skin diseases (including eczemas, lichen ruber, erythrodermia, pyodermia, pemphigus erythematosus, vasculitis, parapsoriasis varioliformis, scleroderma adultorum Buschke, prophyria cutanea tarda, rosacea, dermatomyositis, erythematodes chronicus discoides and indurative tuberculosis), X-ray studies revealed sacroiliac-changes consistent with a low-grade inflammation. This oteoarthritis slightly differs from the patterns disclosed earlier by the same authors in psoriatic patients, lacking any clinical bone or joint symptoms. So far, it has not been possible to explain their nature, cause or development.

Adult↗
PubMed1976

[Chloracne, porphyria cutanea tarda, and other poisonings due to the herbicides].

In 80 industrial workers producing herbicides (2,4,5-trichlorphenoxyaceticacidsodium and sodiumpentachlorphenolate) in Czechoslovakia the following signs of intoxication caused by 2,3,6,7-tetrachlordibenzodioxin were found: Dermatological: Chloracne and Porphyria cutanea tarda. Internal: Disorders of the metabolism of porphyrins, fats, carbohydrates, plasmaproteins. Neurological: Mainly lesions of the peripheral neurone. Psychiatric: Neurasthenic syndrome and organic lesions. Differences from the usual course of chloracne were observed. Porphyria cutanea tarda acquisita was most obvious, one patient suffered and died from severe atherosclerosis, hypertension and diabetes. Many patients developed polyneuropathy, as verified both by EMG and autopsy. Two patients died from bronchogenic carcinoma.

2,4,5-Trichlorophenoxyacetic Acid↗