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Biomedical subjects

L Jensen

Publications and source records attributed to L Jensen.

166 records · Page 10Linked to original sources

Neospora caninum infection and repeated abortions in humans.

To determine whether Neospora caninum, a parasite known to cause repeated abortions and stillbirths in cattle, also causes repeated abortions in humans, we retrospectively examined serum samples of 76 women with a history of abortions for evidence of N. caninum infection. No antibodies to the parasite were detected by enzyme-linked immunosorbent assay, immunofluorescence assay, or Western blot.

Abortion, Habitual↗

Positioning effects on arterial oxygen and relative pulmonary shunt in patients receiving mechanical ventilation after CABG.

OBJECTIVE: To examine the effects of three different positions on arterial oxygen and relative pulmonary shunt in patients after coronary artery bypass graft (CABG) who are receiving mechanical ventilation with an effective tidal volume of 15 ml/kg and a minimum of 5 cm H2O positive end-expiratory pressure. DESIGN: Repeated measures, counterbalanced. SETTING: Adult cardiovascular intensive care unit in a major tertiary referral hospital. SUBJECTS: Convenience sample of 30 patients who had undergone CABG, 90% of whom had postoperative atelectasis. OUTCOME MEASURES: Partial pressure arterial oxygen (PaO2) and relative pulmonary shunt (areas of low ventilation-perfusion ratio). INTERVENTION: Supine, right lateral, and left lateral positions with head of bed elevated 30 degrees. RESULTS: No statistically significant differences in arterial oxygen and relative pulmonary shunt were found among the three positions. CONCLUSIONS: For a selected cohort, positioning may not be an important consideration in arterial oxygenation in patients who have undergone CABG and are receiving mechanical ventilation with a high tidal volume and positive end-expiratory pressure.

Adult↗

Performance of various tests used to screen antibiotic residues in milk samples from individual animals.

The 10-point Milk and Dairy Beef Quality Assurance Program was developed collaboratively by the National Milk Producers Federation and the American Veterinary Medical Association and is designed to promote and document the responsible use of antibiotics in the dairy industry. One area of emphasis in this program is testing of individual animals for antibiotic residues after a specified post-treatment withdrawal time. We examined the performance of various assay systems on milk samples from individual cows. These assays are used at present on bulk tank milk samples by regulatory agencies, processing plants, producers, and veterinarians to detect the presence of beta-lactam antibiotics. A high proportion of false-positive results was obtained for both the pretreatment milk samples from cows with clinical mastitis and the milk samples obtained 21 days after initial therapy (nonantibiotic and antibiotic) for the treatment of mastitis. A high proportion of false-positive outcomes was obtained from the milk of clinically normal cows that had not received any medication for at least 30 days prior to evaluation. The results indicate a serious problem in the use of some assays that were designed to evaluate residues bulk tank milk samples to analyze samples from individual cows. This error in assay specificity results in the unjustifiable discarding of milk that meets regulatory standards and may be misused to accuse the producer or veterinarian of not adhering to regulatory guidelines. Maintaining a safe, high-quality milk supply is a constant goal of the dairy industry, which must be provided the appropriate tools and techniques to meet this challenge.

Animals↗

Preserving the self: women having cardiac surgery.

OBJECTIVE: To explore the process that women undergo when having cardiac surgery. DESIGN: A grounded theory approach was used to gain an understanding of the core process. SETTING: A large community hospital with an active cardiovascular surgery practice and research center. PARTICIPANTS: Ten women, between 21 and 79 years of age, who had undergone cardiac surgery in the last 3 months. RESULTS: Behaviors in which the women were engaged when having cardiac surgery were directed toward "preserving the self" while getting through the surgical experience. This process had five phases: waiting, getting there, surviving, being there, and moving on. Strategies used by these women in preserving the self throughout the phases were: relating, making sense of, managing, and normalizing what was happening to them. CONCLUSION: By having a clearer understanding of the process women undergo when having cardiac surgery, health care providers will be able to participate more effectively with women through their experience.

Adaptation, Psychological↗