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Biomedical subjects

L Jebavý

Publications and source records attributed to L Jebavý.

At least 37 records · Page 2Linked to original sources
PubMed1989

Selective decontamination of the digestive tract in hematological patients (Czechoslovakia-German Democratic Republic cooperative study.

A group of 55 hematological patients treated for the last 2.5 years by the method of selective decontamination was evaluated. Though both institutes (Bad Saarow, Hradec Králové) worked on the problem in the same conditions (indications for the treatment, characteristics of patients, basic drugs), many differences in details were found. However, the important clinical results were the same: A statistically significant decrease in infections and duration of fever in treated patients. A survey of therapy complications, surveillance of infections and incidence of microbes are presented. The evaluation showed that future research including microbiological and immunological investigation based on a standard protocol will be useful.

Adult↗
PubMed1989

[Adverse effects of hemapheresis].

The authors performed 1252 haemaphereses, incl. 689 plasmaphereses. They divide the side-reactions as follows: Technical reaction: these do not threaten the donor directly; these reactions were recorded in 4.4%. Clinical reactions--total 6.8%. a) early, b) late. The authors recorded one severe reaction during plasmapheresis, there was however, no fatality. The most frequent reactions were: general symptoms, failure to withdraw blood because of poor state of the veins and hypotension. The authors analyze the importance of the observed reactions. They used continual separators where in general the incidence of reactions is smaller. They investigated also late reactions, in particular after development of infections in donors or in the staff working with the separator. Repeated donors were subjected to detailed immunological examination, no abnormalities were, however, recorded.

Adult↗
PubMed1989

[Treatment of severely depressed hematopoiesis].

Severe inhibition of haematopoiesis is a serious disease from the prognostic aspect. The authors evaluated a group of 26 patients of whom one survived for more than five years. The mean life span is 154 days. The most frequent cause of death are infectious complications, in particular septicaemia. Investigation of the aetiology of the disease was negative in 46% of the cases, in the remainder drugs were suspected most frequently, in particular antibiotics. It is very important to prevent the development of secondary inhibition of haematopoiesis, in particular by careful indication of myelotoxic drugs. In case of necessity, these drugs should be administered for a short time, in the lowest effective doses with check-ups of the haemogram. Hope for affected patients in future is transplantation of bone marrow and the early administration of antilymphocytic globulin.

Adolescent↗
PubMed1984

A case of 'acute' Waldenström macroglobulinaemia.

A patient with histologically confirmed malignant lymphoma of the non-Hodgkin type with lymphoplasmacellular hyperplasia showed clinical symptoms of Waldenström macroglobulinaemia. A rapid and important increase was observed in the level of IgM lambda paraprotein possessing both cryo- and pyroprecipitative properties. This rise in paraprotein concentration was accompanied by a severe haemorrhagic syndrome. The course of disease was rapid; only six weeks passed from observing the first clinical symptoms to the death of the patient. The failure of combined cytostatic treatment allowed to conclude that the case was one of 'acute' Waldenström macroglobulinaemia.

Adult↗