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Biomedical subjects

L J Taylor

Publications and source records attributed to L J Taylor.

At least 55 records · Page 3Linked to original sources

Antibiotic resistance monitoring, with particular reference to methicillin-resistant Staphylococcus aureus.

Two surveys of antibiotic resistance in hospital pathogens are described. The first is a long-term, multi-center, laboratory based investigation in which antibiotic resistance data from laboratories with computerized reporting is collected. The difficulties of this type of investigation are discussed and some solutions suggested. In the second investigation reports of the isolation of methicillin-resistant Staphylococcus aureus (MRSA) were collected from microbiological laboratories on a nation-wide basis. The results were useful in monitoring the spread of the organism and in its control.

Cross Infection↗

Excision of the proximal end of the femur for hip stiffness in myelomeningocele.

Operation on the hips of patients with myelomeningocele is often followed by stiffness or ankylosis. Excision of the upper end of the femur for this condition frequently fails because of extensive new bone formation. Twelve excisions in eight patients are reported. Six of these patients had recently had spinal fusion operations; the consequent loss of ability to compensate for hip stiffness by spinal flexion had made sitting difficult or impossible. Excision or even re-excision of the upper femur failed in most cases. Careful assessment of hip mobility before spinal operations in these patients is essential and osteotomy rather than excision of the upper femur is advised.

Adolescent↗

Multifocal avascular necrosis after short-term high-dose steroid therapy. A report of three cases.

Avascular necrosis of bone is a well-recognised phenomenon in patients on long-term steroid therapy, especially after renal transplantation. There are only four cases reported in the literature of multifocal avascular necrosis after short-term high-dose steroid therapy, and three additional cases are reported in this paper. All the hips have needed reconstructive surgery within two and a half years of the onset of symptoms; in one patient, however, this has been prevented by other medical problems. In two of the three patients reported in this paper the shoulders also were affected; eventually they became pain-free but movement was restricted. Short-term high-dose steroid therapy has only recently been recognised as a cause of avascular necrosis and attempts should be made to prevent the incidence increasing.

Adult↗

Knodt rod fusion of the lumbar spine.

Thirty-six patients were examined at least 2 years after they underwent Knodt rod distraction fusion of the lumbar spine. Thirty-two patients had a satisfactory clinical result and 23 patients had a solid bone fusion. Six patients had significant complications. It is concluded that Knodt rod distraction fusion is a useful salvage procedure after failed anterior spinal fusion and as a primary procedure in spondylolisthesis.

Adult↗