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Biomedical subjects

L J Fenton

Publications and source records attributed to L J Fenton.

23 records · Page 2Linked to original sources

The determination of aspirin levels in the presence of hyperbilirubinemia.

Many major medical centers are presently utilizing a shortened method (Keller) for determining serum aspirin levels which does not remove interfering compounds. This report documents that the presence of even 1 mg of bilirubin/dl of serum is sufficient to cause a falsely high aspirin level. It is suggested that any method for determining serum bilirubin which does not remove interfering substances constitutes a danger to many groups of patients and should be discontinued.

Aspirin↗

Congenital syphilis after maternal treatment with erythromycin.

A case is reported in which erythromycin was used successfully to treat maternal syphilis but failed to adequately treat the fetus. This report and similar studies suggest that oral erythromycin is not a reasonable alternative drug for the treatment of lues in the penicillin-allergic gravid female.

Adult↗

Blood sampling through umbilical catheters.

An in vitro study testing the reliability of chemical determinations on blood samples withdrawn through an umbilical catheter is described. Blood samples were withdrawn through three different sizes of umbilical catheters containing a solution of dextrose, sodium bicarbonate, and potassium. Using either a 5 French or a 3 1/2 French catheter, accurate results were obtained for pH, sodium, potassium, and glucose when measurements were made after an initial 4-ml blood sample was discarded. With an 8 French catheter, accurate results were obtained for pH, sodium, and potassium but plasma glucose determinations remained inaccurate after 6 ml of blood was discarded.

Blood↗