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Biomedical subjects

L Iglesias-Diez

Publications and source records attributed to L Iglesias-Diez.

5 recordsLinked to original sources
PubMed2000

Photosensitivity induced by oral itraconazole.

A case of photosensitivity induced by itraconazole is reported. A 70-year-old woman had erythema, oedema and vesicles on sun-exposed areas after 5 days of itraconazole treatment for oral candidiasis. Oral photochallenge using itraconazole and sun irradiation was positive, but photopatch test was negative. Photosensitivity from azoles is an uncommon adverse effect. Only three other cases have been described, two induced by ketoconazole and one by itraconazole.

Aged↗
PubMed1993

Primary cutaneous extramedullary plasmacytoma secreting lambda IgG.

An adult male was described, who developed a tumour on his left arm, which was diagnosed as a primary cutaneous extramedullary plasmacytoma after histopathological, electron microscopic and immunocytochemical studies. Further studies ruled out the presence of multiple myeloma, extramedullary plasmacytoma of another site, or paraproteinaemia/paraproteinuria. During a relapse of the tumour 2 1/2 years after initial treatment, a new immunocytochemical study demonstrated that the tumour cells expressed monoclonal lambda IgG at the intracytoplasmic level, an unusual finding.

Humans↗
PubMed1992

Experience with amorolfine in the treatment of dermatomycoses.

In a double-blind randomized comparative study, 75 patients were treated with amorolfine cream 0.125, 0.25 or 0.5%. At the end of treatment clinical cure rates of 80, 76 and 84%, respectively, and mycological cures of 72, 64 and 76% were obtained. At 2 months posttherapy follow-up relapse rates were 0, 12 and 12%, respectively. There was no significant difference between the three groups in terms of clinical and mycological response, duration of treatment or tolerance. In a double-blind parallel study, 40 patients were treated topically with either 0.5% amorolfine cream or 1% bifonazole cream. The percentages of combined clinical and mycological cures were 83.3 and 78.95%, respectively. There was no significant difference in terms of tolerance and clinical and mycological cure rates. All treatments were applied once daily. Posttreatment MIC values did not indicate development of resistance to either amorolfine or bifonazole.

Administration, Topical↗
PubMed1984

Topical ketoconazole (2% dermatological cream) for the treatment of superficial dermatomycoses.

A total of 48 patients with superficial dermatomycoses took part in an open trial to study the efficacy, acceptability and tolerance of topical ketoconazole (2% dermatological cream) applied twice daily. Forty patients (23 women and 17 men) were available for review upon completion of therapy. After 30 days of therapy, 11 patients were cured clinically and mycologically and 5 patients were cured clinically but had positive mycological findings. One of the patients in this group relapsed one month later. After 60 days of treatment, 22 patients were clinically and mycologically cured. Two patients did not respond to treatment. Only 2 patients in this group relapsed one month later.

Administration, Topical↗