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Biomedical subjects

L Ia Abakumova

Publications and source records attributed to L Ia Abakumova.

At least 19 recordsLinked to original sources
PubMed1994

[Extracorporeal detoxication in the treatment of peritonitis complicated with multiple organ insufficiency].

The article deals with experience in the use of filtration and combined methods of extracorporeal detoxification in 201 patients with peritonitis in the phase of polyorganic insufficiency. The methods were developed in the department of abdominal surgery of the Moscow Regional Scientific Research Clinical Institute. The authors show the indications for and the advantages, the mechanisms of the effect, and the results of bifiltration cascade exchange plasmapheresis, improved hemofiltration method, and selective detoxification of portal blood, and the combination of these methods with continuous membrane blood oxygenation. The mortality reduced from 46.6% in the control group to 26.5% in the main group.

Adult↗
PubMed1990

[Determination of groups at risk for laryngeal tumors].

A procedure for development of an adequate screening program for detecting precancer and cancer of the larynx was elaborated on the basis of outpatient charts and regular check-up data. Patients with laryngeal neoplasia were included into the "cancer" group (47), those with hyperplastic laryngitis--"precancer" (189) and disease-free subjects--into the "normal" group (260). Cancer suspects as identified by the procedure should be referred to the otolaryngologist for closer examination.

Age Factors↗
PubMed1990

[Methodological aspects of formation of groups at risk for cancer of the stomach and large intestine].

An algorithm for selection of groups at high risk of cancer of the stomach and colon has been developed with the aim of improving the diagnosis of these diseases in mass screening of the population. A multidimensional statistical analysis realized in MEDSTAT-85 programme package was used to identify the most informative risk factors and to formulate the regularity having these factors expressed in percent by weight. The proposed programme of targeted screening allows for rapid and effective selection of risk groups and, in combination with the conventional gastric and colon fluorography techniques, facilitates timely detection of gastric and colonic cancer.

Aged↗
PubMed1989

[Surgical treatment of patients with cranio-cerebral trauma and the role of neurological symptoms in the prognosis of its outcomes].

Under examination there were 411 patients with cranio-cerebral traumas. A unified method was used at different medical institutions in order to study questions of prognosis of the outcomes. Surgical treatment was used in 117 of them. The investigations have shown that the state of trance-coma both before operation and in the postoperative period is absolutely unfavourable prognostically. The state of trance-coma and the value of 15 scores and less should be taken into consideration as a contraindication for the solution of the question of operation in patients with cranio-cerebral traumas.

Adult↗
PubMed1988

[Information value of initial clinical signs for the prognosis of outcome in the first 24 hours after craniocerebral injury].

The informativeness of clinical indicators for predicting lethal and favourable outcomes during the first 24 hours after a head trauma has been investigated. A pool of clinical findings about the status of 302 patients examined according to a uniform technique has been analyzed using a packet of the MEDSTAT-85 software. The authors present an optimal set of clinical signs for predicting fatal and favourable outcome within the first 24 hours after the trauma with an 83% probability rate.

Brain Injuries↗
PubMed1987

[Prediction of various categories of recovery in craniocerebral injuries and the informative value of clinical signs].

The authors studied the informative value of clinical signs of craniocerebral trauma (CCT) in relation to the prediction of different categories of recovery. Using a package of applied programmes MEDSTAT-85 a clinical pool of the findings about the status of 302 patients examined by a uniform technique was subjected to clinical analysis. The optimal set of clinical indicators for predicting different categories of recovery in the first 24 hours after the CCT with an average accuracy of 80% is described.

Brain Concussion↗
PubMedDate not supplied

[Formalization of the process of differential diagnosis of nevi and initial choroid melanomas with the aid of a diagnostic table].

Basing on the results of a multidimensional discriminant computer-aided analysis of clinical findings in 11 patients with nevi and 102 with initial choroidal Stages TIa-TIb melanomas, the authors suggest formalization of the process of differential diagnosis between nevi and initial choroidal melanomas. For this purpose a diagnostic table with the minimal number of signs was developed. The disease can be diagnosed (the share of erroneous diagnoses is under 6 percent) with the use of just common instruments that can be found in any ophthalmology room.

Choroid Neoplasms↗
PubMedDate not supplied

[Effects of earplugs on the development of hypoacusis and extra-aural pathology in workers exposed to industrial noise].

Using an EC computer and Medstat-85 software, statistical multivariate analysis of data accumulated during 20 years of examinations of 210 workers of a textile (twisting) shop was performed. Out of these subjects 70 persons used antiphones (of ear plugs) continuously, 70 workers used them occasionally, and 70 subjects did not use them at all. It was found that hearing impairment and concomitant vascular disorders developed at an earlier stage and in a greater extent in those workers who never used ear plugs. The noise-induced changes proved more expressed than age-related vascular pathology.

Adolescent↗
PubMedDate not supplied

[The informativeness of clinical laboratory indices of the effectiveness of exchange plasmapheresis in patients with peritonitis].

The results of the application of exchange plasmapheresis in 51 patients with suppurative peritonitis have been processed statistically using "MEDSTAT-85" software. 2-3 exchange plasmapheresis procedures at an up to 2-day interval, with exfusion of 1000-1200 ml plasma and adequate replacement of plasma loss by freshly frozen donor plasma and specific hyperimmune plasma were shown to be an optimum regimen. Blood toxicity, concentration of medium molecular toxins and leukocytic index of intoxication were the most informative criteria of the efficacy of exchange plasmapheresis.

Adult↗
PubMedDate not supplied

[Use of a point-scale assessment of patient status in the surgical treatment of craniocerebral injuries].

The indications and contraindications for surgical treatment in craniocerebral trauma (CCT) were based on estimation of the patient's condition in marks; the dynamics of changes of the results of the estimation in the pre- and postoperative periods were studied. A total of 375 patients with CCT were examined in different medical institutions according to a unified method. Neurosurgical interventions were carried out on 155 patients. All patients who underwent operation when their condition was rated below 15 marks died on the immediate postoperative days, whatever their age and whatever the time of the operation after the trauma. The probability of a favourable outcome increased to 40% in a condition rated 21-30 marks on the day of the operation and reached 69% when it was above 30 marks.

Age Factors↗