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Biomedical subjects

L Horowitz

Publications and source records attributed to L Horowitz.

At least 37 records · Page 2Linked to original sources

Urticaria subsequent to administration of influenza vaccine.

Described is an 11-year-old girl who had a reaction including urticaria and asthma to influenza immunization. The urticaria lasted for nine days. This patient had no clinical sensitivity to egg and no skin test reactivity to egg, but she did show positive skin test reactions to influenza B and bivalent flu vaccine. Since passive transfer did not produce positive skin tests, it would appear that the reactions were not IgE-mediated. The patient has not had subsequent urticaria. The possibility exists of reactions to influenza virus antigens or bacterial or other contaminants of the vaccine. More complete and detailed information about "contaminants" in influenza (and other egg embryo) vaccines should be made available so that these factors can be taken into consideration in seeking the cause of reactions to these vaccines and in possibly preventing reactions.

Allergens↗

The efficacy of cryotherapy in the postoperative shoulder.

We report the results of an outcome study that used visual analog scales to evaluate the efficacy of cryotherapy in the postoperative shoulder. This prospective study included 50 consecutive patients admitted to the hospital for at least one night after anterior shoulder stabilization, rotator cuff repair, or total shoulder replacement. The patients were randomized: 25 were fitted with a cryotherapy device in the operating room, and 25 were not. Otherwise, postoperative treatment was identical for the two groups, including types of analgesic agents given. Visual analog responses were converted to numeric values by simple measurement techniques. The scales assessed pain, comfort, sleep, analgesic use, and overall satisfaction. On the night of the operation the pain was less severe and occurred less often in the cryotherapy group. Those in the cryotherapy group slept better on the night of the operation and perceived the need to use pain medicine less often in comparison with those in the noncryotherapy group. By postoperative day 10 patients in the cryotherapy group reported their shoulders hurt less often and with less severity. Swelling was less, and shoulder movement hurt less during rehabilitation, enhancing the rehabilitative effort. Cryotherapy offers a number of benefits for care of patients in the immediate postoperative period.

Adolescent↗

Observations on the injury mechanism of anterior cruciate ligament tears in skiers.

The purpose of this study was to demonstrate the uniqueness of the injury mechanism for acute complete tears of the anterior cruciate ligament in recreational alpine skiers by using patterns of osseous injury as detected by magnetic resonance imaging. We treated 42 patients (average age, 32 years) who met the following criteria: 1) acute complete anterior cruciate ligament tear incurred during skiing, 2) no history of knee injury, 3) magnetic resonance imaging within 30 days of injury, and 4) arthroscopy and anterior cruciate ligament reconstruction or both for documentation of all intraarticular injury. An osseous injury detected by magnetic resonance imaging was seen in the lateral femoral condyle in 17 (40%) of the patients and was located over the terminal sulcus in 15 of these patients; only 1 had arthroscopic evidence of chondral injury. Four (10%) of the 42 patients had a bone bruise on the medial femoral condyle; all were located at the extreme posterior margin. Thirty-four patients (81%) had a bone bruise on the lateral tibial plateau; 33 were located at the extreme posterior margin and 27 of these were at the posterolateral tibial rim. Twelve patients (29%) had a bone bruise on the medial tibial plateau; all were located on the posterior margin.

Adolescent↗