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Biomedical subjects

L Hooghe

Publications and source records attributed to L Hooghe.

29 records · Page 2Linked to original sources

Cardiovascular effects of methyl methacrylate monomer.

Although cardiorespiratory human sensitivity to circulating methyl methacrylate monomer remains unknown, it is clear that the blood levels responsible for cardiocirculatory alterations in intact dogs are not obtained after insertion of acrylic cement in long bones in clinical practice. Circulating monomer considered as the sole causal factor for the hemodynamic changes described during orthopedic method is highly questionable.

Animals↗

Use of the Hickman catheter as permanent vascular access for hemodialysis.

Nineteen patients in whom it was impossible to create an arteriovenous (AV) fistula were hemodialyzed with adult Hickman catheters as the sole vascular access. Catheter survival was 45% at 1 year, with eight patients requiring two or three catheters for the continuation of their treatment. The probability of a patient still being dialyzed with a Hickman catheter at 1 year was 69%. The calculated risk of developing the most frequent complications was 0.07/100 catheter days for sepsis, 0.4/100 catheter days for thrombosis, and 0.06/100 catheter days for outflow obstruction. These figures seem quite acceptable, and the use of Hickman catheters as permanent vascular access is warranted in this category of difficult patient.

Adult↗

Surgical anatomy of hyperparathyroidism.

The number of glands and the exact location of each normal and pathological parathyroid identified in 416 parathyroidectomies for primary and secondary hyperparathyroidism have been recorded during the last 25 years (1966-1990). Nineteen per cent of all glands were found in ectopic locations. Half of these were distant from the thyroid lobes, most frequently posteriorly alongside the oesophagus, or in the upper anterior mediastinum encapsulated in the thymic remnant. Their discovery required, in some cases, extensive dissections, but a sternotomy was necessary in two cases only. Parathyroid glands may be concealed in the thyroid or in other aberrant locations, more rarely encountered. Supernumerary parathyroids were observed in 5% of cases. They were often pathological and were often in abnormal positions. A sound knowledge of the anatomic variations and of the paths of embryologic migration of the parathyroids are the essential clues for their detection.

Adenoma↗

Granuloma of the distal extremity of the ureter in kidney transplantation.

A granuloma of the distal extremity of the transplanted ureter was diagnosed in 8 of 180 patients operated on according to the Lich-Gregoir technique. This lesion was not observed in 116 patients with Politano-Leadbetter ureterovesical anastomosis nor in 61 patients with a ureterocystostomy constructed according to the technique of De Campos Freire et al. This complication seems to be specific of the Lich-Gregoir technique.

Granuloma↗