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Biomedical subjects

L Holder

Publications and source records attributed to L Holder.

14 recordsLinked to original sources
PubMed1997

The retroisthmic cleft. Scintigraphic appearance and clinical relevance in patients with low back pain.

This article describes the scintigraphic appearance of both a symptomatic and asymptomatic retroisthmic cleft in two athletes with low back pain. This lesion, which involves the lamina, is the least common of the neural arch defects of which spondylolysis is the most common. The anatomy of the lesion is discussed and illustrated. The literature about the possible cause of these lesions is reviewed. The report emphasizes the valuable role of radionuclide bone imaging in patients who have pain of potentially osseous origin, and who have a lesion of uncertain physiologic significance seen on an anatomic study such as a plain x-ray, CT scan, or MRI.

Adult↗
PubMed1990

Allied health education in Oklahoma.

This article is the first of several dealing with medical education and recruitment in Oklahoma and generated at the request of the OSMA-OUHSC Liaison Committee. The articles were sought out and submitted with the assistance of Edward N. Brandt, Jr., MD, PhD, executive dean at the University of Oklahoma College of Medicine.

Allied Health Occupations↗
PubMed1988

Paying for clinical education: fact or fiction?

Changes in the health care system, brought on by cost control measures, are expected to have an impact on clinical education opportunities in allied health. There has been speculation that clinical facilities, upon which academic programs depend for clinical education, will begin charging fees for allowing students to rotate through their facilities. A survey was conducted of 43 schools and colleges of allied health, comprising 274 programs in 46 different disciplines to ascertain the extent to which programs were paying for clinical education. Two basic research questions were addressed: (1) to what extent are academic institutions supporting direct costs for clinical education of students and (2) to what extent are academic institutions exchanging resources with clinical facilities in which their students are receiving clinical education? Data were collected on cash payments made to clinical facilities, payment of preceptors, academic faculty in direct supervision of students in the clinics, tuition credit bank for clinical supervisors, university provision of inservice training for the clinical faculty, and university provision of equipment for use by students in the clinical facility. Results indicate that very few programs are making cash payments--2.2% in academic health centers and 10.6% in non-academic health centers (four-year colleges). In lieu of cash payments, a number of resource exchanges take place between educational institutions and clinical facilities.

Academic Medical Centers↗
PubMed1985

Technetium-99m-pyrophosphate scintigraphy in patients with suspected acute myocardial infarction: impact of interobserver variability.

Technetium-99m-pyrophosphate (TcPYP) scintigraphy may have great value in patients with suspected acute myocardial infarction (AMI), but interobserver variability undoubtedly has adverse impact on predictive value. TcPYP scintigrams for 133 (80%) of 166 consecutive patients admitted for suspected AMI were interpreted independently by three experienced readers. Although there was complete agreement for 87 interpretations (65%), major discrepancies (i.e., at least one positive and one negative reading on the same scan) occurred for 28 scans (21%). To assess predictive accuracy, patients were categorized as follows: 36 had definite AMI manifest by new ECG Q waves and/or CK-MB evidence of AMI (group I), 56 were classified as possible AMI (group II), and 41 had AMI excluded (group III). Using only the definitive diagnostic categories (groups I and III), accuracy for each reader approximated 0.68, with no single reader being correct more often than any other.

Creatine Kinase↗
PubMed1981

Allied health perspectives in the 1980s.

A number of changes taking place in our society are affecting the health care delivery system and influencing allied health education and practice. This article summarizes changes in population characteristics, technology, disease patterns, health care needs, and the programs designed to meet those needs as they influence health personnel development in general and allied health in particular. A current definition of allied health is presented, along with an analysis of allied health personnel in the health care work force and of educational programs preparing allied health personnel. Implications of trends in allied health in the United States are projected and current eras in allied health education are discussed. Finally, the recommendations of the National Commission on Allied Health Education are summarized along the the programmatic response of the American Society of Allied Health Professions.

Allied Health Personnel↗
PubMed1979

The nature of piecemeal necrosis in chronic active hepatitis.

On the basis of histological studies, it is proposed that the type of liver-cell death in piecemeal necrosis is apoptosis. The characteristic inconspicuousness of apoptosis explains why the mode of hepatocyte elimination in piecemeal necrosis has hitherto remained obscure. Cell-mediated immune attack induces apoptosis, not classical necrosis, and the occurrence of apoptosis in piecemeal necrosis links the observed morphological changes in chronic active hepatitis with the other evidence for an autoimmune pathogenesis. It is significant that apoptosis does not evoke inflammation or fibroplasia. In attempting to elucidate the cause of the fibrosis that accompanies progression to cirrhosis in chronic hepatitis, it may thus be more relevant to study the effect on fibroblasts of substances liberated during lymphocyte-hepatocyte interactions than the death of the hepatocytes.

Autoimmune Diseases↗
PubMed1975

A perspective on non-traditional academic programs in the health sciences.

In the 1970s, non-traditional academic programs began to gain impetus, aided by studies and recommendations by such groups as the Carnegie Commission on Higher Education and the Commission on Non-Traditional study. Schools of public health have taken the lead in implementing non-traditional, off-campus programs which are relevant to personnel in health service agencies. Reported in this monograph are three programs representing alternative approaches to off-campus public health programs. As our data base increases and new programs are reported, we may see rapid growth in non-traditional programs, resulting in significant changes in academic programs preparing public health practitioners.

Curriculum↗