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Biomedical subjects

L Heinemann

Publications and source records attributed to L Heinemann.

At least 127 records · Page 7Linked to original sources
PubMed1981

[Epidemiology of venous diseases - results of an epidemiologic study].

48.7% of the population of the district of Dippoldiswalde developed a varicosis. both sexes were affected in the same way with a similar percentage. No side of the legs were preferred. Two thirds of all carriers of varices have only slight varices (small varicose dilatations of the cutaneous veins, reticular varices) without complaints. A considerable varicosis was found in 130/1000 adult inhabitants. Only these carriers of varices can be defined as ill with venous disease. The age is no risk factor of varicosis. The average age of manifestation of varicosis in females is 37.8 years, in males 43.7 years. With growing age, however, the degree of severity of the disease increases.

Adolescent↗
PubMed1981

[Antithrombotic prophylaxis of the complications of arteriosclerosis obliterans].

The clinical efficacy of antithrombolytic drugs in different combinations was studied on a large contingent of patients with cerebral, coronary atherosclerosis and obliterating atherosclerosis of the vessels. It was shown that regular administration of acetylsalicylic acid with coumarin derivatives prolongs life of patients with cardiovascular diseases and decreases the number of vascular catastrophes.

Anticoagulants↗
PubMed1979

[Long-term course of aortic arch syndrome caused by arteriosclerosis].

The course of the extracranially conditioned cerebrovascular disease is characterized by a worse prognosis in comparison with the average population of the GDR (11 years older) and by increased cardiovascular complication rate (every fifth patient suffered a myocardial infarction, every fourth patient suffered an apoplexy). Younger age of manifestation and increasing number of concomitant diseases form the basis of a course which is altogether endangered by complications, which, however, compared with peripheral and coronary arteriosclerosis, is more favourable. Operative reconstruction of the path of a vessel leads to an enduring improvement of the picture of the complaint. The total prognosis corresponds to the so-called spontaneous course. Under permanent treatment with anticoagulants a retardation of the general progressing of arteriosclerosis and improvement of the survival rates is to be proved.

Aged↗
PubMed1979

[Prevention of cardiovascular complications in manifest arteriosclerosis by the use of Micristine].

A long-term clinical trial in micristin-treated patients suffering from organic arterial circulatory disturbances is reported. Problems of therapy monitoring by determination of the ASA level in plasma and of control of platelet aggregation are discussed. Acute cardiovascular complications (myocardial infarction, stroke, acute vascular occlusion, amputation and angiographically demonstrated progression) were observed. The observation time did not suffice to establish statistically significant differences between micristin therapy anticoagulant treatment and basic cardiovascular therapy. The results are suggestive of a more beneficial effect of anticoagulant treatment.

Adenosine Diphosphate↗
PubMed1978

[Reproducibility of the answers of various groups of cardiovascular patients in a standardized questionnaire, differentiated by age and gender].

For the purpose of the valuation of a questionnaire developed by us for the anamnestic recognition of angiocardiopathies, which consists of 63 questions, a repeated interrogation was performed with 220 patients of different age and sex during 14 days. The average reproducibility of the yes/no-decisions was good and varied only slightly in the 8 groups of diseases (86.3--99.4%). The average degree of reproducibility referred to the sexes is nearly the same (94.7% and 95.5%, respectively). Referred to the age groups the highest reproducibility was established in the patients older than 60 years (95.7%) and the lowest in patients between 50 and 60 years (93.3%).

Aged↗
PubMed1977

[Use of a computer for the preparation of medical history screening in cardiovascular diseases].

Questionable data may be regarded as significant indicators for a screening. It is the aim of our investigations to develop a screening standard anamnesis in form of a questionaire which allows on the scale of larger groups of population to establish the number of endangered persons and patients who probably suffer from cardiovascular diseases but of the quantity of apparantly healthy persons. In order to recognize regularities of the diagnostics coordination of the individual patient by his answers on the questionnaire the data of 400 diagnostically clarified persons (model experiment) underwent a discriminancy analysis. When the data of unknown test persons are given in, on account of the well-known functions of discriminancy a classification in the groups persons with heart and circulatory diseases or with a healthy heart and circulation or a group diagnosis can be performed, respectively. The evaluation of the data of unknown test persons of a pilot study in 96% resulted in a correct classification in patients with heart and circulatory diseases or persons with healthy heart and circulation, the classification in the above mentioned groups of diagnosis was performed on an average to 57%.

Cardiovascular Diseases↗
PubMed1975

[Qualification of anamnestic data for cardiovascular screening].

The projecting of an anamnestic questionnaire concerning angiocardiopathies for purposes of screening for the 8 most important groups of angiocardiopathies was performed in two simultaneous stages--model experiments and population experiment. In the model stage, which is the topic of this paper, apart from investigations of reproducibility and controls of voluntary falsifications of answers above all an examination concerning the significance of the data was carried out. The methods used for this--analysis of the complaints of typical groups of patients (analysis of discriminancy) and analysis of experiences of recognized experts of angiocardiopathies (scale graduation of symptoms)--were discussed and first results described.

Cardiovascular Diseases↗
PubMed1975

[Screening and early diagnosis of disorders of the arterial blood supply].

After a short reference to the significance of the screening examinations and early diagnosis for the secondary prevention in disease of the heart and the circulatory system the authors give a survey on the methods of screening examinations and the early diagnosis bening at disposal nowadays in organic disturbances of the arterial bloods supply. Anamnestic, clinical and paraclinical methods are cited, in which cases the paraclinical methods are subdivided into haemostasiological, haemodynamic and biochemical examinations.

Arteriosclerosis↗