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Biomedical subjects

L Hartmann

Publications and source records attributed to L Hartmann.

At least 181 records · Page 10Linked to original sources

Apartheid medicine. Health and human rights in South Africa.

Human rights and health care under apartheid in South Africa were studied. Human rights violations, such as detention without charge or trial, assault and torture in police custody, and restriction orders, have had devastating effects on the health of persons experiencing them. These violations have occurred in the context of a deliberate policy of discriminatory health care favoring the white minority over the black majority. South Africa's medical societies have had mixed responses to the health problems raised by human rights violations and inequities in the health care system. The amelioration of health care for all and prevention of human rights violations depend on ending apartheid and discrimination and greater government attention to these problems.

Delivery of Health Care↗

Quality of life and pain in patients with recurrent breast and gynecologic cancer.

Pain is a central factor affecting quality of life for the cancer patient. This descriptive study was designed to explore the relationship between pain and several factors affecting quality of life. The factors explored included physical and social functioning, emotional health, and spiritual commitment in women with recurrent breast or gynecologic cancer. Pain frequency, amount, and interference with activities were found to correlate more strongly with objective measures of quality of life (i.e., physical and social functioning) than subjective measures (i.e., psychological or spiritual dimensions).

Adult↗

[Bifidobacterium adolescentis suppresses the humoral immune response to an autochthonous intestinal bacterium--experiments with gnotobiotic rats].

On the basis of association-experiments with gnotobiotic rats, we described the immunogenicity of two selected bacterial species (Bifidobacterium adolescentis and Bacteroides thetaiotaomicron). B. adolescentis is a gram-positive lactic acid producing bacterium, strains of which are claimed to have probiotic properties. B. thetaiotaomicron is a gram-negative rod, autochthonous to the human as well as to the rats' intestinal tract. Colonization of the gut was monitored by determination of bacterial cell counts in the animals' feces. In order to investigate the systemic immune reaction, the amounts of specific serum-IgG and -IgA against both bacterial species were measured in the serum. The intestinal immune reaction was examined by measuring the specific IgA in the rats' feces. Knowing about the antibody levels in gnotobiotic rats induced by monoassociation we subsequently disassociated two groups of rats in order to investigate the impact of B. adolescentis on the immune reaction against B. thetaiotaomicron. One group was disassociated simultaneously with B. adolescentis and B. thetaiotaomicron, the second group was disassociated with these bacteria in sequence. B. adolescentis was merely able to induce a mucosal immune reaction, while B. thetaiotaomicron challenged the mucosal as well as the systemic immune system. Furthermore B. adolescentis obviously suppressed the systemic and mucosal immune reaction against the autochthonous B. thetaiotaomicron.

Actinomycetales Infections↗