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Biomedical subjects

L Haber

Publications and source records attributed to L Haber.

9 recordsLinked to original sources
PubMed2001

Decreased bone mineral density in Prader-Willi syndrome: comparison with obese subjects.

Bone density, anthropometric data, and markers of bone turnover were collected on 21 subjects diagnosed with Prader-Willi syndrome (PWS) and compared with 9 subjects with obesity of unknown cause. In addition, urinary N-telopeptide levels were obtained in all subjects. N-telopeptides are the peptide fragments of type I collagen, the major bone matrix material. During periods of active bone degradation or high bone turnover, high levels of N-telopeptides are excreted in the urine. However, no significant difference was detected in the urinary N-telopeptide levels when corrected for creatinine excretion (raw or transformed data) between our subjects with obesity or PWS and the observed effect size of the between-group difference was small. Although N-telopeptide levels were higher but not significantly different in the subjects with PWS compared with obese controls, the subjects with PWS had significantly decreased total bone and spine mineral density and total bone mineral content (all P < 0.001). No differences in N-telopeptide levels or bone mineral density were observed between subjects with PWS and chromosome 15q deletion or maternal disomy. Thus, decreased bone mineral density in subjects with PWS may relate to the lack of depositing bone mineral during growth when bones are becoming more dense (e.g., during adolescence), possibly because of decreased production of sex or growth hormones and/or long-standing hypotonia. It may not be caused by loss, or active degradation, of bone matrix measurable by the methods described in this study further supporting the possible need for hormone therapy during adolescence.

Adolescent↗
PubMed1993

Comparison of nine methods of indicating the direction to objects: data from blind adults.

Nine methods of indicating the direction to object locations were tested on twenty blind adult subjects. The task was to indicate the location of active auditory targets distributed in a semicircle with a 1.7 m radius around the subject. Target location, practice, and feedback were systematically varied for each method. The greatest accuracy and lowest variability were found for pointing methods that used body parts (directing the nose at the target, facing it with the chest, and pointing with the index finger) and extensions of body parts (pointing with a hand-held cane or with a short stick). Two less accurate methods involved rotating a dial. The least accurate methods involved drawing and a verbal description in terms of clockface labels. Method interacted significantly with target location, and with individual differences. In general, the body-part and extension method were affected less than other methods by target location and individual differences. The findings suggest that a pointing response that uses body part or an extension of a body part is the best choice for experimental or diagnostic measurement of object location by blind subjects. Differences between the results of this study of blind subjects and auditory localization accuracy in sighted subjects are discussed, and the implications for spatial processing in the blind are considered.

Adult↗
PubMed1975

Pulmonary talc embolization.

A young woman with a history of drug abuse rapidly developed cor pulmonale, restrictive pulmonary defect, low diffusion capacity, and a suggestion of left ventricular dysfunction. She died from complications after a lung biopsy. Microscopic examination showed talc granulomas and arteritis. Some form of closed biopsy is probably safer, and trial of corticosteroid therapy seems warranted for this diagnosis. Talc ia a dangerous ingredient for any oral preparation that is likely to be used parenterally.

Adult↗
PubMedDate not supplied

Collection and storage of data for evoked potential studies: a database.

A detailed description of a set of programs is presented which is designed for use with subjects tested in a research laboratory primarily with visual evoked potentials (VEPs). It has been written in a way which accommodates other modalities such as brain-stem auditory evoked potentials (BAEPs) and somatosensory evoked potentials (SEPs). It can be used in a clinic or a hospital for collecting patient information, data recordings, and analysis. The programs are implemented on an LSI-11/23 microcomputer and allow for initial subject data entry, entry of data acquired at subsequent visits, data analysis, lists of patient files and data sorts and tabulations. In their present form they are intended to be run by a staff who have little experience with computers and technical skills.

Computers↗
PubMedDate not supplied

A description of the Maternal Addiction Program of the University of Miami/Jackson Memorial Medical Center.

The MAP of the University of Miami/Jackson Memorial Medical Center/Highland Park Pavilion is a comprehensive inpatient and outpatient chemical dependency rehabilitation program that serves mostly lower socioeconomic, African-American perinatal substance-abusing women. The multidisciplinary treatment team incorporates a broad spectrum of group and individual therapeutic modalities, including 12-step, psychoeducational, and RP components. Within MAP programs, significant attention is given to issues and experiences that are unique to this population and that must be addressed if rehabilitation is to be successful. These topics include, but are not limited to, physical, emotional and sexual abuse, empowerment, family and parenting concerns, and HIV prevention and coping skills for HIV-seropositive women.

Academic Medical Centers↗
PubMedDate not supplied

Ecological transition: using Bronfenbrenner's model to study sexual identity change.

Bronfenbrenner's (1979) ecological transition model provides a framework to study coming out in lesbians. The model takes into account activities such as sexual behavior, perceptions of the behavior, and social context in which behavior takes place. The importance of context makes this model useful in identifying possible connections between sexual identity alterations and larger social forces. Interventions based on this framework can reduce stress and promote health during coming out.

Female↗
PubMedDate not supplied

Nursing program to meet the challenge of caring for patients with water intoxication.

This article describes a program that is effective in working with psychiatric patients who have trouble with excessive water intake. The purpose of the program is to provide consistent treatment in a controlled and therapeutic environment in which the special needs of these patients can be met. We incorporate a variety of nursing interventions suggested by the literature to help meet the goals of the program. As a result of the program, disruptive behavior has decreased and patients have learned skills to help them manage their illness. An additional benefit of the program is that working with water intoxication patients is no longer stressful for staff.

Hospital Units↗