Arthography and arthroscopy in the small hospital.
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Arthrography↗
Biomedical subjects
L H Winkler
Publications and source records attributed to L H Winkler.
Myasthenia gravis: pathogenesis, diagnosis, and therapy.
Myasthenia gravis most commonly affects the ocular muscles. Abnormal fatigability of the involved muscle groups is the most remarkable feature of the physical examination. Recent studies have demonstrated that a thymus-derived antibody plays a role in the pathogenesis of myasthenia gravis, which is now thought to be an autoimmune disorder. Its association with other autoimmune disorders has been recognized for some time. A high index of suspicion is the most essential element in diagnosis. Rapid and reproducible response to administration of anticholinesterase leaves little doubt of the diagnosis, but characteristic EMG findings in myasthenic muscle evoked by repetitive stimulation of peripheral motor nerve are definitive. Anticholinesterase drugs are the mainstay of therapy. Thymectomy is indicated in patients with thymoma and in some young persons with serious disease. Patients who respond poorly to anticholinesterase therapy or surgery are candidates for steroid therapy.
Adult↗
Space colonization--some physiological perspectives.
While the establishment of large self-sustaining communities in free space is possible with present day technology, our understanding of the physiological design criteria determining habitat mass, structural configuration, cost, and ultimate feasibility, is inadequate. This paper briefly summarizes the biomedical findings of an engineering workshop cosponsored by the American Society of Engineering Education, Stanford University, and NASA's Ames Research Center (Summer, 1975). It is the conclusion of the study that a viable, economically productive space community of 10,000 people could be established with very conservative, centrifugally generated earth-normal gravity, general population maximum ionizing radiation dose standards (i.e. less than or equal to 0.5 rem/year, using passive shielding techniques), and a normoxic but reduced nitrogen partial pressure atmosphere. It is the conclusion of the author that although, in theory, some of the physiological constraints might in certain cases be partially relaxed, extensive research must be done to establish the degree of any such relaxation.
Atmosphere↗