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Biomedical subjects

L H Gold

Publications and source records attributed to L H Gold.

At least 91 records · Page 5Linked to original sources

Polyvinyl foam embolization of vascular and neoplastic lesions of the head, neck, and spine.

Embolization of vascular and neoplastic lesions of the head, neck, and spine may be performed either as primary therapy (particularly for lesions which are difficult to approach surgically) or preoperatively to decrease blood loss. Polyvinyl alcohol foam (PAF) offers a number of advantages over other embolic material, including biocompatibility, promotion of progressive thrombosis and fibrosis, permanence, compressibility, and manageability. The clinical cases illustrate the kinds of lesions that are amenable to embolization, including arteriovenous malformations, arteriovenous fistulas, meningiomas, and nasopharyngeal tumors. Techniques and possible complications are discussed.

Adolescent↗

The New York rubella incident: a case for changing hospital policy regarding rubella testing and immunization.

A case of rubella in a male obstetrics-gynecology house staff member exposed 170 staff members and 11 prenatal patients to the clinical disease. Of 163 staff members tested within one week of exposure, 132 (80 per cent) were not susceptibles. Repeat titres three weeks later on 28 susceptibles remained negative. Of the 11 patients exposed, three were susceptible and none seroconverted.

Adult↗

Effective atomic number and electron density as measured with a computed tomography scanner: computation and correlation with brain tumor histology.

The mathematical basis and methodology for determining the effective atomic number and electron density of a tissue are presented. Cranial computed tomography (CT) scanning is performed at two different energy levels, both with and without contrast enhancement. The histology of 15 brain tumors has been correlated with the effective atomic number and electron density of the tumor, with parameters of the linear attenuation coefficient, and with statistical values of the CT numbers. The most useful value in separating gliomas from meningiomas from metastases appears to be the percentage change of effective atomic number following contrast enhancement.

Absorptiometry, Photon↗

A protocol for the use of contrast enhancement in cranial computed tomography.

There is some confusion regarding the indications for and methodology of the use of contrast material in cranial computed tomography. Some authors recommend a nonenhanced scan in all cases, followed by an enhanced scan if indicated by the symptoms or the appearance of the unenhanced scan. Others have questioned the value of the nonenhanced scan in patients with tumor. The authors offer a protocol for the use of contrast material. Possible tumor patients are scanned with contrast material alone; other patients are scanned either (a) without contrast material or (b) both with and without contrast material, depending upon the most likely clinical diagnosis.

Adult↗

The nonspecificity of absorption coefficients in the differentiation of solid tumors and cystic lesions.

Eleven lesions of the brain were analyzed and compared; they had absorption coefficients uniformly at the cerebrospinal fluid (CSF) level following contrast enhancement, and ranged from benign to malignant and solid to cystic. Grossly solid tumors may have absorption coefficients on the CT scan equal to CSF even after contrast enhancement. Absorption coefficients are misleading as histological indicators and in diagnosis; it is impossible to separate cystic from non-cystic, benign from malignant, and neoplastic from non-neoplastic lesions by absorption coefficients alone.

Absorption↗

Periventricular spread of tumor demonstrated by computed tomography.

Spread of intracranial neoplasms through the periventricular tissues of the brain is well known to neuropathologists, but is almost never recognized by the usual neuroradiologic techniques of angiography and pneumoencephalography. Periventricular tumor spread can, however, be readily dmonstrated by contrast-enhanced CT scanning. This report documents 4 cases of periventricular tumor diagnosed by CT scanning.

Adult↗

Angiographic diagnosis of intra- and extraaxial tumors in the cerebellopontine angle.

Angiography is an effective diagnostic modality in the evaluation of patients with suspected cerebellopontine angle tumor, particularly when there is not a clear clinical differentiation between an intraaxial and an extraaxial mass, or when the patient presents with increased intracranial pressure. In a series of 17 extraaxial masses in the cerebellopontine angle and 2 cerebellar tumors which presented into the angle, the most common angiographic findings were: 1. elevation and/or medial displacement of the proximal portions of the superior cerebellar artery; this finding was seen only in the extraaxial tumors and has not been demonstrated with intraaxial masses; 2. downward, medial, and posterior displacement of the proximal portions of the posterior inferior cerebellar artery; 3. lateral displacement and stretching of the hemispheric branches of both the superior cerebellar and posterior inferior cerebellar arteries; and 4. displacement of the vein of the lateral recess and of the petrosal vein either downward and medially or upward and laterally.

Brain Neoplasms↗