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Biomedical subjects

L H GARLAND

Publications and source records attributed to L H GARLAND.

At least 55 records · Page 3Linked to original sources

Cancer detection; a county medical society program, Riverside, California.

Cancer detection examinations by physicians in their private offices were performed as a county medical society project for a period of one year.In a series of 6,765 patients examined, approximately 600 were found to have lesions clinically suspect for tumor. The total number of proven cancers discovered was 280 and the number of lesions classified as precancerous was 87. This percentage of tumors discovered compares favorably with reports from special cancer detection centers formerly utilized in other parts of the country. The Cancer Commission believes that periodic health examinations of persons over the age of 40 in the offices of private physicians is a practical approach to the problem of earlier detection of tumors at accessible sites-the tumors that are the most readily curable by current surgical and radiotherapeutic techniques.

California↗

Radiological aspects of collagen diseases.

The collagen diseases, an ill-defined group of clinical entities, have as their basis a generalized alteration of the connective tissue, especially of its extracellular components. They include periarteritis nodosa, disseminated lupus erythematosus, dermatomyositis, scleroderma, rheumatic fever and rheumatoid arthritis. The radiological findings in a series of cases of these diseases were reviewed. In 28 cases of periarteritis, 20 cases showed some abnormal findings in the thorax. These included pleural effusions, pulmonary changes, pericardial effusions and cardiac enlargement. In 32 cases of disseminated lupus erythematosus, thoracic findings were noted in 21. They resembled the changes found in periarteritis. In some 25 cases of scleroderma, diverse radiological findings were noted. These included "cystic" changes in the lungs (one case) and pulmonary "hives." In the intestinal tract esophageal and small bowel alterations were found, both ectatic and stenotic. In the soft tissues of the "pressure areas" variable degrees of calcification were observed. Dermatomyositis is the rarest of the collagen disease group; only one autopsy-proven case is available for study. Chest x-rays taken a year before death showed slight cardiac enlargement. The lungs were clear. In acute rheumatic fever, x-ray examination may disclose pericardial or pleural effusion, and so-called rheumatic pneumonitis; the latter has no specific diagnostic features. Soft tissue swellings may develop around some of the joints. In rheumatoid arthritis, joint changes are numerous and fairly characteristic, and are followed in many cases by fibrous or bony ankylosis and deformities of considerable degree. Awareness of the commoner radiological changes in this entire group of diseases should result in earlier establishment of diagnosis, especially in the more obscure examples.

Arthritis, Rheumatoid↗