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Biomedical subjects

L H Epstein

Publications and source records attributed to L H Epstein.

At least 181 records · Page 10Linked to original sources

Smoking and carbon monoxide levels during pregnancy.

Self-reports of smoking status and breath tests for carbon monoxide were collected in prenatal outpatients. The breath test for carbon monoxide appeared to be a valid and specific measure of smoking status during pregnancy. Of the 179 patients surveyed, 99 reported they had smoked during the present pregnancy. Nineteen of the smokers reported they had quit during the present pregnancy and 46 reported that they smoked fewer cigarettes than at the beginning of their pregnancy. Most of the quitters and reducers stated that they had stopped or reduced their intake early in pregnancy and for pregnancy-related reasons; however, neither parity, nausea or vomiting, marital status, nor requests of physicians or family were associated with higher rates of smoking cessation or reduction. Most of the pregnant smokers were interested in stopping smoking, but few attended a free treatment program.

Adult↗

Relationships among measures of smoking topography.

Interrelationships between puffing, puff duration, puff volume, and heart rate change were assessed in a sample of 63 chronic, high rate smokers. Results showed puff duration and volume were related for males and females, and that heart rate change was related to volume in males and puff duration in females. Puffs were not related to either volume or heart rate change in males or females. These results call into question research on smoking behavior which does not measure volume, and shows that components of puffing may not be used interchangeably, and that neither puffs nor puff duration are accurate predictors of volume of intake.

Adult↗

The relationship between muscle discrimination ability and response to relaxation training in three kinds of headaches.

Accurate discrimination of changes in physiological response has been noted as an important element in learning to control that response. Using a magnitude production procedure involving forearm isometric contractions, it was found that the ability to discriminate muscle tension varied across headache groups, with the no-headache control group (r = .76) being most accurate, followed by the tension group (r = .68), the mixed tension and migraine group (r = .60), and finally the migraine group (r = .51). The most important result, however, was that muscle discrimination ability significantly predicted clinical outcome from treatment by relaxation training for tension headache subjects (r = .50) but did not predict outcome for migraine or mixed headache subjects.

Arm↗

The effects of targeting improvements in urine glucose on metabolic control in children with insulin dependent diabetes.

A treatment program designed to increase the percentage of negative urine tests was implemented using a multiple-baseline across groups design in a sample of 19 families of children with insulin dependent diabetes. The treatment involved instruction in insulin adjustment, decrease in intake of simple sugars and saturated fats, and increase in exercise, along with teaching the parents to support improvements in children's self-regulatory behaviors using a point economy and praise. New procedures designed to measure and reinforce adherence to the urine testing regimen were developed. Results showed significant increases in percentage of negative urines consistent with implementation of treatment across the three treatment groups, which were maintained over the follow-up period. Metabolic measures of control, including glycosylated hemoglobin and serum glucose did not show improvements even though the relationship between the percentage of negative urine tests and glycosylated hemoglobin was very high during treatment.

Behavior Therapy↗

An experimental analysis of discrimination of pulse transit time.

The present study attempted to determine if individuals could be trained to discriminate changes in their own pulse transit time, an indirect estimate of relative (systolic) blood pressure. A single-subject ABAB reversal-reinstatement design was used in an experimental analysis of the effects of feedback on pulse transit time discrimination in a normotensive and essential hypertensive subject. Subjects engaged a response button on a free-operant schedule each time they felt pulse transit time was momentarily below a predetermined mean. After baseline, visual feedback was provided contingent on correct responses (feedback) and incorrect responses (reversal). Procedures also assessed the role of respiration as a possible discriminative stimulus. For both subjects discrimination improved during feedback, showed disruption when the reversal was implemented, and subsequently improved during the second feedback phase. Respiration did not appear to have served as the discriminative stimulus. Results are discussed in terms of the need for refining procedures, especially to ensure generalization to no-feedback conditions, and the potential applications and importance of training of pulse transit time.

Adult↗